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SML1943

Sigma-Aldrich

FPMINT

≥98% (HPLC)

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Synonym(s):
4-((4-(2-Fluorophenyl)piperazin-1-yl)methyl)-6-imino-N-(naphthalen-1-yl)-1,3,5-triazin-2-amine, 6-[[4-(2-Fluorophenyl)-1-piperazinyl]methyl]-N2-1-naphthalenyl-1,3,5-triazine-2,4-diamine
Empirical Formula (Hill Notation):
C24H24FN7
CAS Number:
Molecular Weight:
429.49
NACRES:
NA.77

Quality Level

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

FC(C=CC=C1)=C1N2CCN(CC3=NC(NC4=C(C=CC=C5)C5=CC=C4)=NC(N)=N3)CC2

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This Item
SML2472SML2631SML0262
FPMINT ≥98% (HPLC)

Sigma-Aldrich

SML1943

FPMINT

UPGL00004 ≥98% (HPLC)

Sigma-Aldrich

SML2472

UPGL00004

IITZ-01 ≥98% (HPLC)

Sigma-Aldrich

SML2631

IITZ-01

GSK575594A ≥98% (HPLC)

Sigma-Aldrich

SML0262

GSK575594A

form

powder

form

powder

form

powder

form

powder

color

white to beige

color

white to pink

color

white to beige

color

white to beige

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: ≥5 mg/mL

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

100

Biochem/physiol Actions

FPMINT is a potent, irreversible and non-competitive inhibitor of equilibrative nucleoside transporters ENT1 and ENT2. FPMINT is more selective for ENT2 than ENT1.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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25G
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705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

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Philip C T Tang et al.
European journal of pharmacology, 791, 544-551 (2016-10-30)
Equilibrative nucleoside transporters (ENTs) play a crucial role in the transport of nucleoside and nucleoside analogues, which are important for nucleotide synthesis and chemotherapy. In addition, ENTs regulate extracellular adenosine levels in the vicinity of its receptors and hence influence

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