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SML2027

Sigma-Aldrich

L-2-oxothiazolidine-4-carboxylic acid propargyl amide

≥98% (HPLC)

Synonym(s):

(R)-2-Oxo-N-2-propyn-1-yl-4-thiazolidinecarboxamide, OTC propargyl amide, OTC-PA

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5 MG
$69.39

$69.39

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About This Item

Empirical Formula (Hill Notation):
C7H8N2O2S
CAS Number:
2165706-30-7
Molecular Weight:
184.22
MDL number:
MFCD30729654
UNSPSC Code:
12352106
NACRES:
NA.77

$69.39

List Price$73.20Save 5%
Web-Only Promotion

Available to ship onApril 15, 2025Details

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

H2O: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

C#CCNC([C@@H]1CSC(N1)=O)=O

InChI

1S/C7H8N2O2S/c1-2-3-8-6(10)5-4-12-7(11)9-5/h1,5H,3-4H2,(H,8,10)(H,9,11)/t5-/m0/s1

InChI key

MWEQVHWJNCRXGP-YFKPBYRVSA-N

Biochem/physiol Actions

L-2-oxothiazolidine-4-carboxylic acid propargyl amide is a cell penetrant, potent and selective competitive inhibitor of cystathionine-γ-lyase that completely abrogated L-cysteine-induced vasorelaxation in tissue.
cell penetrant, potent and selective competitive inhibitor of cystathionine-γ-lyase

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Angela Corvino et al.
Scientific reports, 6, 34398-34398 (2016-10-07)
Hydrogen sulfide is an essential catabolite that intervenes in the pathophysiology of several diseases from hypertension to stroke, diabetes and pancreatitis. It is endogenously synthesized mainly by two pyridoxal-5'-phosphate-dependent enzymes involved in L-cysteine metabolism: cystathionine-ß-synthase (CBS) and cystathionine-γ-lyase (CSE). Research

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