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SML2637

NPD8733

≥98% (HPLC)

Synonym(s):

N-[2-(4-Methoxybenzoyl)-3-benzofuranyl]acetamide

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5 MG

$77.43

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About This Item

Empirical Formula (Hill Notation):
C18H15NO4
CAS Number:
Molecular Weight:
309.32
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder

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SMILES string

N(c1c2c([o]c1C(=O)c3ccc(cc3)OC)cccc2)C(=O)C

InChI key

NQZBUYPGHZTWIR-UHFFFAOYSA-N

InChI

1S/C18H15NO4/c1-11(20)19-16-14-5-3-4-6-15(14)23-18(16)17(21)12-7-9-13(22-2)10-8-12/h3-10H,1-2H3,(H,19,20)

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

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This Item
SML1639SML2682SML1927
form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 10 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 10 mg/mL, clear

color

white to beige

color

white to beige

color

faint brown to very dark brown-red

color

white to beige

Biochem/physiol Actions

NPD8733 is an inhibitor of cancer cell-enhanced fibroblast migration. NPD8733 binds to valosin-containing protein (VCP)/p97.
inhibitor of cancer cell-enhanced fibroblast migration

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Kruthi Suvarna et al.
The Journal of biological chemistry, 294(9), 2988-2996 (2019-01-06)
Carcinoma-associated fibroblasts are fibroblasts activated by surrounding cancer cells. Carcinoma-associated fibroblasts exhibit enhanced cell migration, which plays an important role in cancer metastasis. Previously, we demonstrated enhanced migration of NIH3T3 fibroblasts when they were cultured in the presence of MCF7

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