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SML2736

Sigma-Aldrich

NPBA

≥98% (HPLC)

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Synonym(s):
N-(2-((4-nitro-2-(trifluoromethyl)phenyl)amino)ethyl)benzamide
Empirical Formula (Hill Notation):
C16H14F3N3O3
CAS Number:
Molecular Weight:
353.30
MDL number:

Quality Level

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

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NPBA ≥98% (HPLC)

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SML2736

NPBA

MP-A08 ≥98% (HPLC)

Sigma-Aldrich

SML2657

MP-A08

BRD3308 ≥98% (HPLC)

Sigma-Aldrich

SML1639

BRD3308

SM1-71-R ≥98% (HPLC)

Sigma-Aldrich

SML2739

SM1-71-R

form

powder

form

powder

form

powder

form

powder

color

white to beige

color

white to beige

color

white to beige

color

white to beige

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 10 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

Biochem/physiol Actions

NPBA is a potent and selective agonist (activator) of potassium K2P channel TASK-3 (KCNK9).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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25G
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705578-5MG-PW

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1000309185

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Fuyun Tian et al.
Molecular pharmacology, 96(1), 26-35 (2019-04-25)
The TASK-3 channel is a member of the K2P family that is important for the maintenance of the resting membrane potential. Previous studies have demonstrated that the TASK-3 channel is involved in several physiologic and pathologic processes, including sleep/wake control

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