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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 mg | Check Cart for Availability | $104.00 | |
| 25 mg | Check Cart for Availability | $420.00 |
About This Item
Empirical Formula (Hill Notation):
C47H70N6O8 · xC2HF3O2
Molecular Weight:
847.09 (free base basis)
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
$104.00
Check Cart for Availability
Quality Level
assay
≥95% (HPLC)
form
film
color
white to beige
shipped in
wet ice
storage temp.
−20°C
SMILES string
N([C@@H](CO)C(=O)OC)C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)c4ccc(cc4)C(C)(C)C)Cc3ccccc3)C)CC(C)C)CCCCN(C1C2CC(C1)CC2)C
InChI key
UKWNWTBRKZUHGX-GKUWNYOMSA-N
Biochem/physiol Actions
UNC4976 is a cell penetrant and potent positive allosteric modulator (PAM) of CBX7 chromodomain of polycomb repressive complex 1 that enhances CBX7 chromodomain affinity for nucleic acids. UNC4976 substantially potentiates the expression of polycomb target genes.
cell penetrant and potent positive allosteric modulator (PAM) of CBX7 chromodomain
1 of 1
This Item | |||
|---|---|---|---|
| form film | form film or powder | form lyophilized powder (white) | form lyophilized powder |
| assay ≥95% (HPLC) | assay ≥95% (HPLC) | assay ≥98% (HPLC) | assay ≥95% (HPLC) |
| Quality Level 100 | Quality Level 100 | Quality Level - | Quality Level 100 |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| shipped in wet ice | shipped in - | shipped in wet ice | shipped in - |
| color white to beige | color white to yellow | color white to off-white | color white to beige |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Kelsey N Lamb et al.
Cell chemical biology, 26(10), 1365-1379 (2019-08-20)
Polycomb-directed repression of gene expression is frequently misregulated in human diseases. A quantitative and target-specific cellular assay was utilized to discover the first potent positive allosteric modulator (PAM) peptidomimetic, UNC4976, of nucleic acid binding by CBX7, a chromodomain methyl-lysine reader
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SML2912-25MG | 04061842664696 |
| SML2912-5MG | 04061842664702 |



