SML3057

Indacaterol

Name: Indacaterol
Brand: SIGMA
Price: 64.3 USD
Availability: InStock

≥98% (HPLC)

Synonym(s):

5-[(1R)-2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-2(1H)-quinolinone, QAB-149, R)-5-[2-(5,6-diethylindan-2-ylamino)-1-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one

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About This Item

Empirical Formula (Hill Notation):

C₂₄H₂₈N₂O₃

CAS Number:

312753-06-3

Molecular Weight:

392.49

UNSPSC Code:

12352200

NACRES:

NA.77

MDL number:

MFCD18782702

Assay:

≥98% (HPLC)

Form:

powder

Quality level:

100

Key Documents

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InChI

1S/C24H28N2O3/c1-3-14-9-16-11-18(12-17(16)10-15(14)4-2)25-13-22(28)19-5-7-21(27)24-20(19)6-8-23(29)26-24/h5-10,18,22,25,27-28H,3-4,11-13H2,1-2H3,(H,26,29)/t22-/m0/s1

SMILES string

O[C@@H](CNC1CC(C=C(CC)C(CC)=C2)=C2C1)C3=CC=C(O)C(N4)=C3C=CC4=O

InChI key

QZZUEBNBZAPZLX-QFIPXVFZSA-N

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

Quality Level

100

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Show Differences

1 of 4

This Item	SML3126	SML1953	SML3178
Sigma-Aldrich SML3057 Indacaterol	Sigma-Aldrich SML3126 BI-2852	Sigma-Aldrich SML1953 GDC-0879	Sigma-Aldrich SML3178 CPS2
assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay ≥98% (HPLC)
form powder	form powder	form powder	form powder
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C
solubility DMSO: 2 mg/mL, clear	solubility DMSO: 2 mg/mL, clear	solubility DMSO: 2 mg/mL, clear (warmed)	solubility DMSO: 2 mg/mL, clear
color white to beige	color white to beige	color white to beige	color white to beige

Biochem/physiol Actions

Indacaterol is an ultra-long-acting beta-adrenoceptor agonist. It is used as bronchodilator.

Ultra-long-acting beta-adrenoceptor agonist; bronchodilator

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number

0000413791

0000413794

0000275246

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Impact of Phosphodiesterase 4 Inhibition on the Operational Efficacy, Response Maxima, and Kinetics of Indacaterol-Induced Gene Expression Changes in BEAS-2B Airway Epithelial Cells: A Global Transcriptomic Analysis.

Radhika Joshi et al.

Molecular pharmacology, 96(1), 56-72 (2019-05-01)

The effects of phosphodiesterase (PDE) 4 inhibitors on gene expression changes in BEAS-2B human airway epithelial cells are reported and discussed in relation to the mechanism(s) of action of roflumilast in chronic obstructive pulmonary disease (COPD). Microarray-based gene expression profiling

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Indacaterol