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MilliporeSigma

SML3170

Sigma-Aldrich

QPD-Otf

≥98% (HPLC)

Synonym(s):

4-chloro-2-(6-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)phenyl trifluoromethanesulfonate

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$115.00
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$370.00

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Estimated to ship onJuly 14, 2025Details


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5 MG
$115.00
25 MG
$370.00

About This Item

Empirical Formula (Hill Notation):
C15H7Cl2F3N2O4S
CAS Number:
Molecular Weight:
439.19
UNSPSC Code:
12352200
NACRES:
NA.77

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$115.00


Estimated to ship onJuly 14, 2025Details


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Technical Service
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Quality Level

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

O=C1NC(C2=C(C=CC(Cl)=C2)OS(=O)(C(F)(F)F)=O)=NC3=CC=C(C=C31)Cl

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Show Differences

1 of 4

This Item
SML3542SML3195PZ0375
QPD-Otf ≥98% (HPLC)

SML3170

QPD-Otf

AZD0530 ≥98% (HPLC)

SML3195

AZD0530

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

room temp

solubility

DMSO: 2 mg/mL, clear (warmed)

solubility

DMSO: 2 mg/mL, clear (Warmed)

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

color

white to beige

color

white to beige

color

white to beige

color

white to beige

Biochem/physiol Actions

QPD-OTf is a cell penetrant activity-based fluorogenic substrate for kinesin-1 that apparently binds to the nucleotide-binding site which removes triflate caging causing precipitation and crystallization of fluorescent QPD along microtubule cytoskeleton marking a kinesin-1 path from Golgi apparatus toward the cell periphery. QPD-OTf is not a substrate for Eg5.
cell penetrant activity-based fluorogenic substrate for kinesin-1

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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