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SRP0328

Sigma-Aldrich

PADI-3 human

recombinant, expressed in baculovirus infected Sf9 cells, ≥60% (SDS-PAGE)

Synonym(s):
Peptidyl arginine deiminase, type III
NACRES:
NA.32

biological source

human

recombinant

expressed in baculovirus infected Sf9 cells

Assay

≥60% (SDS-PAGE)

form

aqueous solution

mol wt

75 kDa

packaging

pkg of 10 μg

storage condition

avoid repeated freeze/thaw cycles

concentration

0.25 mg/mL

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... PADI3(51702)

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SRP0327SRP0153SRP0427
PADI-3 human recombinant, expressed in baculovirus infected Sf9 cells, ≥60% (SDS-PAGE)

Sigma-Aldrich

SRP0328

PADI-3 human

PADI-2 human recombinant, expressed in baculovirus infected Sf9 cells, ≥60% (SDS-PAGE)

Sigma-Aldrich

SRP0327

PADI-2 human

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in baculovirus infected insect cells

recombinant

expressed in baculovirus infected Sf9 cells

assay

≥60% (SDS-PAGE)

assay

≥60% (SDS-PAGE)

assay

≥50% (SDS-PAGE)

assay

≥88% (SDS-PAGE)

form

aqueous solution

form

aqueous solution

form

aqueous solution

form

aqueous solution

mol wt

75 kDa

mol wt

77 kDa

mol wt

50 kDa

mol wt

106 kDa

packaging

pkg of 10 μg

packaging

pkg of 10 μg

packaging

pkg of 20 μg

packaging

pkg of 5 μg

General description

Human PADI-3, also known as Peptidyl arginine deiminase, type III, (GenBank Accession No. NM_016233), amino acids 1-664 (end) with C-terminal FLAG-tag, MW= 75 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Application

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Sijun Dong et al.
The Biochemical journal, 397(3), 449-459 (2006-05-05)
Human peptidylarginine deiminase type III gene (PADI3) encodes a crucial post-translational modification enzyme that converts protein-bound arginine residues into citrulline residues. Its expression is restricted to a few cell types, including keratinocytes in the granular layer of the epidermis and
Rachida Nachat et al.
The Journal of investigative dermatology, 124(2), 384-393 (2005-01-29)
Post-translational conversion of arginine to citrulline residues is catalyzed by peptidylarginine deiminases (PAD). Although the existence of five isoforms of PAD has been reported in rodents and humans, their tissue distribution, substrate specificity, and physiological function have yet to be
T Kanno et al.
The Journal of investigative dermatology, 115(5), 813-823 (2000-11-09)
Peptidylarginine deiminase catalyzes the post-translational modification of proteins through the conversion of arginine to citrulline in the presence of calcium ions. In rodents, peptidylarginine deiminase has been classified into four isoforms, types I, II, III, and IV, which are distinct

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