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SRP0372

Sigma-Aldrich

MKK6 active human

recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE)

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Synonym(s):
MAP2K6, MEK6, mitogen-activated protein kinase kinase 6
NACRES:
NA.32

biological source

human

recombinant

expressed in baculovirus infected Sf9 cells

Assay

≥80% (SDS-PAGE)

form

aqueous solution

mol wt

63.5 kDa

packaging

pkg of 20 μg

storage condition

avoid repeated freeze/thaw cycles

concentration

1.36 mg/mL

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... MAP2K6(5608)

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This Item
M5814SRP0249SRP0251
MKK6 active human recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE)

Sigma-Aldrich

SRP0372

MKK6 active human

PLK2 Active human recombinant, expressed in baculovirus infected insect cells, ≥60% (SDS-PAGE)

Sigma-Aldrich

SRP0249

PLK2 Active human

STK33 Active human recombinant, expressed in baculovirus infected insect cells, ≥65% (SDS-PAGE)

Sigma-Aldrich

SRP0251

STK33 Active human

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in E. coli

recombinant

expressed in baculovirus infected insect cells

recombinant

expressed in baculovirus infected insect cells

assay

≥80% (SDS-PAGE)

assay

≥80% (SDS-PAGE)

assay

≥60% (SDS-PAGE)

assay

≥65% (SDS-PAGE)

form

aqueous solution

form

buffered aqueous solution

form

aqueous solution

form

aqueous solution

mol wt

63.5 kDa

mol wt

81 kDa

mol wt

calculated mol wt 107 kDa

mol wt

84 kDa

storage condition

avoid repeated freeze/thaw cycles

storage condition

-

storage condition

avoid repeated freeze/thaw cycles

storage condition

avoid repeated freeze/thaw cycles

General description

Human MKK6 (GenBank Accession No. NM_002758.3), amino acids 2-end with N-terminal GST-tag, MW=63.5 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Application

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Carlo Serra et al.
Molecular cell, 28(2), 200-213 (2007-10-30)
During muscle regeneration, the mechanism integrating environmental cues at the chromatin of muscle progenitors is unknown. We show that inflammation-activated MKK6-p38 and insulin growth factor 1 (IGF1)-induced PI3K/AKT pathways converge on the chromatin of muscle genes to target distinct components
T L Lotan et al.
The Journal of pathology, 212(4), 386-394 (2007-06-20)
Identification of the signalling cascades that are differentially activated during prostatic tumourigenesis is a crucial step in the search for future molecular targets in this disease. The stress-activated protein kinase (SAPK) signalling cascade culminates in the phosphorylation of the JNK

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