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SRP0414

Sigma-Aldrich

PKLR Var2 active human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

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Synonym(s):
PK1, PKL, RPK, pyruvate kinase, liver and RBC
CAS Number:
UNSPSC Code:
12352200
NACRES:
NA.32

biological source

human

recombinant

expressed in E. coli

assay

≥90% (SDS-PAGE)

form

aqueous solution

mol wt

59 kDa

packaging

pkg of 20 μg

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... PKLR(5313)

General description

PKR (GenBank Accession No. NM_181871) full length, amino acids 2-543 (end) with N-terminal His-tag, MW=59 kDa, expressed in an E. coli expression system.

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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María J Bullido et al.
Neurobiology of aging, 29(8), 1160-1166 (2007-04-11)
Sporadic Alzheimer's disease (AD) appears to be the consequence of the interaction between combinations of genes and environmental factors (for example virus infections). To test this hypothesis, we are examining human genes relevant to herpes simplex virus type 1 (HSV-1)
Steven T Russell et al.
Experimental cell research, 315(1), 16-25 (2008-11-01)
Treatment of murine myotubes with high glucose concentrations (10 and 25 mM) stimulated protein degradation through the ubiquitin-proteasome pathway, and also caused activation (autophosphorylation) of PKR (double-stranded-RNA-dependent protein kinase) and eIF2alpha (eukaryotic initiation factor 2alpha). Phosphorylation of PKR and eIF2alpha

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