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SRP0476

Sigma-Aldrich

SMARCA2 (1375-1511) human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

Synonym(s):
BRM, SNF2, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2, SWI2, Sth1p
NACRES:
NA.32

biological source

human

recombinant

expressed in E. coli

Assay

≥90% (SDS-PAGE)

form

aqueous solution

mol wt

16.9 kDa

packaging

pkg of 100 μg

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... SMARCA2(6595)

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This Item
SRP0475SRP0467SRP0480
recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

assay

≥90% (SDS-PAGE)

assay

≥90% (SDS-PAGE)

assay

≥90% (SDS-PAGE)

assay

≥82% (SDS-PAGE)

form

aqueous solution

form

aqueous solution

form

aqueous solution

form

aqueous solution

mol wt

16.9 kDa

mol wt

16.4 kDa

mol wt

15.5 kDa

mol wt

16.2 kDa

packaging

pkg of 100 μg

packaging

pkg of 100 μg

packaging

pkg of 100 μg

packaging

pkg of 100 μg

General description

Human Bromodomain SMARCA2 or BRM (GenBank Accession No. NM_003070) amino-acids 1375 – 1511 with N-terminal HIS-tag, MW = 16.9 kDa, expressed in an E. coli expression system.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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A Hunter Shain et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(5), E252-E259 (2012-01-12)
Defining the molecular genetic alterations underlying pancreatic cancer may provide unique therapeutic insight for this deadly disease. Toward this goal, we report here an integrative DNA microarray and sequencing-based analysis of pancreatic cancer genomes. Notable among the alterations newly identified
G Liu et al.
Oncogene, 30(29), 3295-3304 (2011-04-12)
SWI/SNF (SWItch/sucrose non-fermentable) complexes are ATP-dependent chromatin remodeling enzymes critically involved in the regulation of multiple functions, including gene expression, differentiation, development, DNA repair, cell adhesion and cell cycle control. BRM, a key SWI/SNF complex subunit, is silenced in 15-20%

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