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SRP0483

Sigma-Aldrich

CREBBP (1081-1197) His tag human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

Synonym(s):
CBP, CREB binding protein, KAT3A, RSTS
NACRES:
NA.32

biological source

human

recombinant

expressed in E. coli

Assay

≥90% (SDS-PAGE)

form

aqueous solution

mol wt

14.9 kDa

packaging

pkg of 100 μg

storage condition

avoid repeated freeze/thaw cycles

concentration

1.26 mg/mL

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... CREBBP(1387)

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This Item
SRP0468SRP0466SRP0465
recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

assay

≥90% (SDS-PAGE)

assay

≥90% (SDS-PAGE)

assay

≥90% (SDS-PAGE)

assay

≥90% (SDS-PAGE)

form

aqueous solution

form

aqueous solution

form

aqueous solution

form

aqueous solution

mol wt

14.9 kDa

mol wt

14.8 kDa

mol wt

14.9 kDa

mol wt

15.8 kDa

packaging

pkg of 100 μg

packaging

pkg of 100 μg

packaging

pkg of 100 μg

packaging

pkg of 100 μg

General description

Human bromodomain CREB binding protein (CREBBP), also known as CBP, RSTS and KAT3A (GenBank Accession No. NM_004380) amino acids 1081- 1197 with N-terminal His-tag, MW=14.9 kDa, expressed in an E. coli expression system.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Wei-Chien Huang et al.
Molecular cell, 26(1), 75-87 (2007-04-17)
CBP plays a central role in coordinating and integrating multiple signaling pathways. Competition between NF-kappaB and p53 for CBP is a crucial determinant of whether a cell proliferates or undergoes apoptosis. However, how the CBP-dependent crosstalk between these two transcription
I Panagopoulos et al.
Human molecular genetics, 10(4), 395-404 (2001-02-07)
The CBP gene at 16p13 fuses to MOZ and MLL as a result of the t(8;16)(p11;p13) in acute (myelo)monocytic leukemias (AML M4/M5) and the t(11;16)(q23;p13) in treatment-related AML, respectively. We show here that a novel t(10;16)(q22;p13) in a childhood AML

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