All Photos(1)



Fgf-2 from mouse

recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC)

FGF-b, Fibroblast Growth Factor-basic, HBGF-2 Prostatropin
MDL number:

biological source



expressed in E. coli


≥95% (HPLC)
≥95% (SDS-PAGE)



mol wt

~16.3 kDa


pkg of 50 μg

storage condition

avoid repeated freeze/thaw cycles


endotoxin, tested

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.


Gene Information

mouse ... Fgf2(14173)

General description

FGF-2 (fibroblast growth factor 2) is a basic heparin binding growth factor. It is ubiquitously expressed and belongs to the FGF family. It is also referred to as BFGF (basic fibroblast growth factor). The recombinant mouse FGF-2 is a single, non-glycosylated chain containing 145 amino acids and having a molecular weight of 16.3kDa.

Biochem/physiol Actions

FGF-2 (fibroblast growth factor 2, also referred to as BFGF (basic fibroblast growth factor)) stimulates the proliferation of a wide variety of cells including mesenchymal, neuroectodermal and endothelial cells. It is present in the preimplantation embryos and is important for proper development. It is also responsible for angiogenesis. FGF-2 plays a crucial role in adipogenesis and development of adipose tissues. It is associated with tumor growth and metastasis.

Physical form

Sterile filtered and Lyophilized without additives.


Reconstitute in sterile water to 100 μg/mL.
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Storage Class Code

11 - Combustible Solids



Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Yongyi Wang et al.
PloS one, 7(7), e40691-e40691 (2012-08-01)
In fertile women, the endometrium undergoes regular cycles of tissue build-up and regression. It is likely that uterine stem cells are involved in this remarkable turn over. The main goal of our current investigations was to identify slow-cycling (quiescent) endometrial
Interleukin-1? induces fibroblast growth factor 2 expression and subsequently promotes endothelial progenitor cell angiogenesis in chondrocytes.
Chien SY
Clinical Science, 130, 667-681 (2016)
Biphasic effects of FGF2 on adipogenesis.
Kim S
PLoS ONE, 10, e0120073-e0120073 (2015)
Blocking FGF2 with a new specific monoclonal antibody impairs angiogenesis and experimental metastatic melanoma, suggesting a potential role in adjuvant settings.
de Aguiar RB
Cancer Letters, 371, 151-160 (2016)
Binding of FGF2 to FGFR2 in an autocrine mode in trophectoderm cells is indispensable for mouse blastocyst formation through PKC-p38 pathway.
Yang J
Cell Cycle, 14, 3318-3330 (2015)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service