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MilliporeSigma

SRP5076

Sigma-Aldrich

PTPN6, active, GST tagged human

recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym(s):

HCP, HCPH, HPTP1C, PTP-1C, SH-PTP1, SHP-1, SHP-1L

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$402.00

About This Item

UNSPSC Code:
12352200
NACRES:
NA.32

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$402.00

Usually ships in 2 weeks.
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Technical Service
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recombinant

expressed in E. coli

assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

specific activity

820-1110 nmol/min·mg

mol wt

~93 kDa

NCBI accession no.

NM_080548

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... PTPN6(5777)

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PTPN6, active, GST tagged human recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

SRP5076

PTPN6, active, GST tagged human

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PTPN13 (2169-2485), active, GST tagged human recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

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PTPN13 (2169-2485), active, GST tagged human

PTPN2, active, GST tagged human recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

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PTPN2, active, GST tagged human

Gene Information

human ... PTPN6(5777)

Gene Information

human ... PTPN1(5770)

Gene Information

human ... PTPN13(5783)

Gene Information

human ... PTPN2(5771)

assay

≥70% (SDS-PAGE)

assay

≥70% (SDS-PAGE)

assay

≥70% (SDS-PAGE)

assay

≥70% (SDS-PAGE)

specific activity

820-1110 nmol/min·mg

specific activity

2125-2875 nmol/min·mg

specific activity

2040-2760 nmol/min·mg

specific activity

6928-9372 nmol/min·mg

recombinant

expressed in E. coli

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in E. coli

recombinant

expressed in E. coli

form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

mol wt

~93 kDa

mol wt

~71 kDa

mol wt

~61 kDa

mol wt

~69 kDa

General description

PTPN6 gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The noncatalytic N-terminus of this PTP can interact with MAP kinases and negatively regulates ERK2 and p38 MAP-kinases activity. The PTPN6 was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway.

Physical form

Supplied in 20mM MOPS, pH 7.5, 50mM NaCl, 10mM glutathione, 0.25mM DTT, 0.1mM PMSF, 30% glycerol.

Preparation Note

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
W233-3

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