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SRP6191

Sigma-Aldrich

SAA1 monkey

recombinant, expressed in E. coli, ≥97% (SDS-PAGE)

Synonym(s):
Amyloid fibril protein AA, Amyloid protein A, MGC111216, PIG4, SAA, SAA2, Serum amyloid A protein, TP53I4
NACRES:
NA.32

biological source

Monkey

recombinant

expressed in E. coli

assay

≥97% (SDS-PAGE)

form

lyophilized

mol wt

11.8 kDa

packaging

pkg of 50 μg

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

Monkey ... SAA(6288)

General description

SAA1 protein is an acute phase apolipoprotein reactant which is produced mostly by hepatocytes and under regulation of inflammatory cytokines. SAA1 (Serum amyloid A1) protein is produced mainly in the liver and circulates in low levels in the blood. The SAA1 seems to have a role in the immune system. SAA1 protein levels increase in the blood and other tissues under conditions of inflammation. SAA1 may facilitate the repair of injured tissues; it also acts as an antibacterial agent, and signals the migration of germ-fighting cells to sites of infection. SAA1 also functions as an apolipoprotein of the HDL complex. Elevated levels of SAA1 ultimately affect secondary amyloidosis, extracellular amassing of amyloid fibrils, resulting from a circulating precursor, in a variety of tissues and organs. The most widespread type of amyloidosis appears secondary to chronic inflammatory disease, mainly rheumatoid arthritis. SAA1 monkey recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 104 amino acids and having a total molecular mass of 11.8 kDa. SAA1 is purified by proprietary chromatographic techniques

Physical form

Lyophilized from a sterile filtered solution containing PBS pH 7.4.

Reconstitution

Reconstitute in sterile ddH₂O to a concentration ≥ 100 μg/mL. This solution can then be diluted into other aqueous buffers.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

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Certificate of Origin

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