MilliporeSigma
All Photos(1)

Documents

SRP6370

Sigma-Aldrich

Aldolase A human

recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

Sign Into View Organizational & Contract Pricing

Synonym(s):
ALDA, ALDOA, Fructose bisphosphate Aldolase A, GSD12
NACRES:
NA.32

biological source

human

recombinant

expressed in E. coli

assay

≥95% (SDS-PAGE)

form

liquid

mol wt

41.5 kDa (384 aa, 1-364 aa + His Tag)

packaging

pkg of 100 μg

concentration

1 mg/mL

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... ALDOA(226)

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
SRP6323SRP6371SAB1409002
Aldolase A human recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

SRP6370

Aldolase A human

Pentraxin 3 human recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

SRP6323

Pentraxin 3 human

Aldose Reductase human recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

SRP6371

Aldose Reductase human

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

-

biological source

human

biological source

human

biological source

human

biological source

mouse

concentration

1 mg/mL

concentration

1 mg/mL

concentration

1 mg/mL

concentration

-

form

liquid

form

liquid

form

liquid

form

buffered aqueous solution

mol wt

41.5 kDa (384 aa, 1-364 aa + His Tag)

mol wt

44.4 kDa (401 aa, 18-381 aa + His Tag)

mol wt

35.8 kDa (316 aa, 1-316 aa)

mol wt

antigen 33.99 kDa

General description

Aldolase A (ALDOA) is a ubiquitous glycolytic enzyme expressed in developing embryos and in adult muscles. The gene encoding it is localized on human chromosome 16p11.2. Recombinant human Aldolase A, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Biochem/physiol Actions

In glycolysis, aldolase A (ALDOA) catalyzes the reversible reaction of fructose-1,6-bisphosphate to glyceraldehydes-3-phosphate and dihydroxyacetone phosphate. It is involved in a wide range of cellular functions such as maintenance of striated muscle contraction, cell shape and mobility, actin filament organization and ATP biosynthetic process. High expression level of ALDOA is reported in various forms of malignant cancers, including human lung squamous, renal cell and hepatocellular carcinomas. ALDOA deficiency causes myopathy and hemolytic anemia.

Physical form

1 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 100 mM NaCl and 10% glycerol.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Human aldolase A deficiency associated with a hemolytic anemia: thermolabile aldolase due to a single base mutation.
Kishi H
Proceedings of the National Academy of Sciences of the USA, 84(23) (1987)
Fructose-bisphosphate aldolase a is a potential metastasis-associated marker of lung squamous cell carcinoma and promotes lung cell tumorigenesis and migration.
Sha Du
PLoS ONE, 9(9) (2014)
Comparative proteomics analysis of gastric cancer stem cells.
Morisaki T
PLoS ONE, 9(14) (2014)
Association and Mutation Analyses of 16p11.2 Autism Candidate Genes
Ravinesh A
PLoS ONE (2009)
Two cases of red cell aldolase deficiency associated with hereditary hemolytic anemia in a Japanese family.
Miwa S
American Journal of Hematology, 11(4) (1981)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service