Skip to Content
MilliporeSigma
All Photos(1)

Documents

SRP6506

Sigma-Aldrich

Haptoglobin Plasma (MixedType) from human plasma

≥95% (SDS-PAGE)

Synonym(s):

Bp, Haptoglobin b-Chain, Hp, haptoglobin a-chain

Sign Into View Organizational & Contract Pricing


About This Item

UNSPSC Code:
12352202
NACRES:
NA.32

biological source

human plasma

assay

≥95% (SDS-PAGE)

form

lyophilized

mol wt

monomer 200 kDa (Hp 2-1)
monomer 400 kDa (Hp 2-2)
monomer 86 kDa (Hp 1-1)

packaging

pkg of 1 mg

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... HP(3240)

General description

An acute-phase plasma protein found in human plasma at 100-300 mg/100 mL. Binds hemoglobin, thus preventing loss of iron through the kidneys. Humans are polymorphic for haptoglobin, with three major phenotypes: Hp 1-1, Hp 2-1, and Hp 2-2. While the phenotypic distribution can vary greatly between ethnicities and geographic location, the Hp 2-1 phenotype is the most prevalent phenotype in humans. Plasma concentrations of haptoglobin are highest in individuals with Hp 1-1, intermediate in Hp 2-1 individuals, and lowest in Hp 2-2 individuals. Hp 1-1 is the most effective at binding hemoglobin, and Hp 2-2 is the least effective. This functional difference may be associated with the frequency and severity of epilepsy attacks, as researchers have found a correlation between recurring seizures and the Hp 2-2 phenotype.

Physical form

Lyophilized as a salt-free solid.

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service