SRP6506
Haptoglobin Plasma (MixedType) from human plasma
≥95% (SDS-PAGE)
Synonym(s):
Bp, Haptoglobin b-Chain, Hp, haptoglobin a-chain
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About This Item
UNSPSC Code:
12352202
NACRES:
NA.32
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This Item | 372022 | SRP6316 | F0162 |
|---|---|---|---|
| assay ≥95% (SDS-PAGE) | assay ≥95% (SDS-PAGE) | assay ≥95% (SDS-PAGE) | assay ≥90% (SDS-PAGE) |
| biological source human plasma | biological source - | biological source human | biological source human plasma |
| form lyophilized | form lyophilized | form lyophilized | form lyophilized powder |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| packaging pkg of 1 mg | packaging - | packaging pkg of 100 μg, pkg of 500 μg | packaging pkg of 0.5 mg |
| Gene Information human ... HP(3240) | Gene Information - | Gene Information human ... SERPINC1(462) | Gene Information human ... FN1(2335) |
General description
An acute-phase plasma protein found in human plasma at 100-300 mg/100 mL. Binds hemoglobin, thus preventing loss of iron through the kidneys. Humans are polymorphic for haptoglobin, with three major phenotypes: Hp 1-1, Hp 2-1, and Hp 2-2. While the phenotypic distribution can vary greatly between ethnicities and geographic location, the Hp 2-1 phenotype is the most prevalent phenotype in humans. Plasma concentrations of haptoglobin are highest in individuals with Hp 1-1, intermediate in Hp 2-1 individuals, and lowest in Hp 2-2 individuals. Hp 1-1 is the most effective at binding hemoglobin, and Hp 2-2 is the least effective. This functional difference may be associated with the frequency and severity of epilepsy attacks, as researchers have found a correlation between recurring seizures and the Hp 2-2 phenotype.
Physical form
Lyophilized as a salt-free solid.
Storage Class
13 - Non Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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