All Photos(4)

T0625

Sigma-Aldrich

Taurine

≥99%

Synonym(s):
2-Aminoethanesulfonic acid
Linear Formula:
NH2CH2CH2SO3H
CAS Number:
Molecular Weight:
125.15
Beilstein:
1751215
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.32

Quality Level

biological source

synthetic

assay

≥99%

form

powder

application(s)

cell analysis: suitable

color

white

mp

>300 °C (lit.)

storage temp.

room temp

SMILES string

NCCS(O)(=O)=O

InChI

1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)

InChI key

XOAAWQZATWQOTB-UHFFFAOYSA-N

Gene Information

human ... GRIN1(2902)
rat ... Ppm1a(24666)

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General description

Taurine (2-aminoethanesulphonic acid) is predominantly found in the retina and heart and is also found in the brain, intestine, skeletal muscles and kidneys.

Application

Taurine has been used for the isolation and growth of taurine-utilizing purple non-sulfur bacteria and in phototrophic growth experiments.

Packaging

10 mg in poly bottle
1 kg in poly bottle
10, 25, 100, 500 g in poly bottle

Biochem/physiol Actions

Non-selective endogenous agonist at glycine receptors. Conditionally essential sulfonated amino acid which modulates apoptosis in some cells; functions in many metabolic activities; a product of methionine and cysteine metabolism.
Taurine modulates the concentration of intracellular calcium, protects against ischemia-reperfusion injury and possesses blood pressure-lowering properties. It also has a role in bile formation and fat digestion. Deficiency of taurine is associated with anxiety, hyperactivity, epilepsy and depression.

Storage Class Code

13 - Non Combustible Solids

WGK Germany

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Phototrophic utilization of taurine by the purple nonsulfur bacteria Rhodopseudomonas palustris and Rhodobacter sphaeroides.
Novak RT
Microbiology, 150(Pt 6), 1881-1891 (2004)
The potential health benefits of taurine in cardiovascular disease.
Xu YJ
Experimental and Clinical Cardiology, 13(2), 57-65 (2008)
Felizia K Voss et al.
Science (New York, N.Y.), 344(6184), 634-638 (2014-05-03)
Regulation of cell volume is critical for many cellular and organismal functions, yet the molecular identity of a key player, the volume-regulated anion channel VRAC, has remained unknown. A genome-wide small interfering RNA screen in mammalian cells identified LRRC8A as...
Deniz Tasdemir et al.
Bioorganic & medicinal chemistry, 15(21), 6834-6845 (2007-09-04)
The type II fatty acid pathway (FAS-II) is a validated target for antimicrobial drug discovery. An activity-guided isolation procedure based on Plasmodium falciparum enoyl-ACP reductase (PfFabI) enzyme inhibition assay on the n-hexane-, the CHCl(3-) and the aq MeOH extracts of...
Zi-Bing Jin et al.
PloS one, 6(2), e17084-e17084 (2011-02-25)
Retinitis pigmentosa (RP) is the most common inherited human eye disease resulting in night blindness and visual defects. It is well known that the disease is caused by rod photoreceptor degeneration; however, it remains incurable, due to the unavailability of...

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