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T0632

Sodium thioglycolate

≥96.5% (iodometric)

Synonym(s):

Mercaptoacetic acid sodium salt, Thioglycolic acid sodium salt

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25 g

Estimated to ship TODAYfromMILWAUKEE

$59.40
100 g

Estimated to ship TODAYfromMILWAUKEE

$98.80
500 g

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$378.00

About This Item

Linear Formula:
HSCH2COONa
CAS Number:
367-51-1
Molecular Weight:
114.10
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
24899901
EC Number:
206-696-4
Beilstein/REAXYS Number:
4569109
MDL number:
MFCD00043386

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assay

≥96.5% (iodometric)

form

powder

color

white to off-white

useful pH range

6.7 (20 °C, 100 g/L)

mp

>300 °C (lit.)

solubility

water: ~609.1 g/L at 20 °C (OECD Test Guideline 105)

storage temp.

−20°C

SMILES string

[Na+].[O-]C(=O)CS

InChI

1S/C2H4O2S.Na/c3-2(4)1-5;/h5H,1H2,(H,3,4);/q;+1/p-1

InChI key

GNBVPFITFYNRCN-UHFFFAOYSA-M

Application

Sodium thioglycolate has been used:
  • as a growth supplement in enrichment media and to study its effect on Arcobacter
  • in influenza hemagglutinin formulation in order to reduce disulfide-mediated cross-linking and early potency loss
  • in electron microscopy

Biochem/physiol Actions

Sodium thioglycolate acts as reducing agent and is suitable for anaerobic and microaerophilic bacterial growth.
Sodium thioglycolate is a commonly used reagent for bacteriological research to maintain reducing conditions in media. Thioglycolate can also protect enzymes against inactivation by maintaining protein thiol groups in the reduced state. Thioglycolate medium is frequently used in inflammation research to elicit a neutrophil and macrophage response in vivo.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Disclaimer

At room temperature, concentrations over 70% in water tend to form 1-2% thioglycolides per month which hydrolyze to the original free compound when made acidic or alkaline. The 70% solution oxidizes in air but is stable at room temperature when tightly closed. Thioglycolate salts may also lose purity on storage. The exclusion of air does not materially improve stability.

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1 of 1

This Item
O0136379735C4945
Sodium thioglycolate ≥96.5% (iodometric)

Sigma-Aldrich

T0632

Sodium thioglycolate

Sodium oxalate BioXtra

Sigma-Aldrich

O0136

Sodium oxalate

Sodium oxalate ≥99.99% trace metals basis

Sigma-Aldrich

379735

Sodium oxalate

Sodium cacodylate trihydrate BioXtra, ≥98%

Sigma-Aldrich

C4945

Sodium cacodylate trihydrate

assay

≥96.5% (iodometric)

assay

≥99.0% (titration)

assay

≥99.99% trace metals basis

assay

≥98%

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

solubility

water: ~609.1 g/L at 20 °C (OECD Test Guideline 105)

solubility

-

solubility

-

solubility

H2O: 0.5 M, clear, colorless

form

powder

form

powder

form

powder

form

powder

storage temp.

−20°C

storage temp.

-

storage temp.

-

storage temp.

room temp

useful pH range

6.7 (20 °C, 100 g/L)

useful pH range

-

useful pH range

-

useful pH range

-

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pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Aquatic Chronic 3 - Met. Corr. 1 - Skin Sens. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SDBB8178
SDBB8181
SDBB8180
SDBB8173
SDBB8520

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Global Trade Item Number

SKUGTIN
T0632-500G04061835367993
T0632-25G04061835367986
T0632-100G04061835367979

Questions

1–2 of 2 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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