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T1502

Sigma-Aldrich

Triethanolamine hydrochloride

≥99.5% (titration)

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Synonym(s):
2,2′,2′′-Nitrilotriethanol hydrochloride, Tris(2-hydroxyethyl)amine hydrochloride
Linear Formula:
(HOCH2CH2)3N · HCl
CAS Number:
Molecular Weight:
185.65
Beilstein:
3909940
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

Quality Level

Assay

≥99.5% (titration)

form

crystalline powder

useful pH range

7.3-8.3

pKa (25 °C)

7.8

mp

177-179 °C (lit.)

solubility

water: 0.333 g/mL, clear, colorless

application(s)

diagnostic assay manufacturing

SMILES string

Cl.OCCN(CCO)CCO

InChI

1S/C6H15NO3.ClH/c8-4-1-7(2-5-9)3-6-10;/h8-10H,1-6H2;1H

Inchi Key

HHLJUSLZGFYWKW-UHFFFAOYSA-N

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1 of 4

This Item
T953420928790279
Triethanolamine hydrochloride BioXtra, ≥99.5% (titration)

Sigma-Aldrich

T9534

Triethanolamine hydrochloride

Premium Grade
Triethanolamine ≥99.0% (GC)

Sigma-Aldrich

90279

Triethanolamine

-
form

crystalline powder

form

powder

form

-

form

liquid, viscous liquid

mp

177-179 °C (lit.)

mp

177-179 °C (lit.)

mp

-

mp

17.9-21 °C (lit.)

solubility

water: 0.333 g/mL, clear, colorless

solubility

H2O: 1 M, clear, colorless

solubility

-

solubility

H2O: 1 M, clear, colorless

application(s)

diagnostic assay manufacturing

application(s)

diagnostic assay manufacturing

application(s)

-

application(s)

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

General description

Triethanolamine (TEA) belongs to the family of ethanolamine. It includes the properties of both amines and alcohols. Addition of TEA to an acidic buffer facilitates the determination of fluoride in inorganic orthophosphates by using a fluoride-selective electrode.

Application

Triethanolamine hydrochloride has been used:
  • in the preparation of triethanolamine buffer
  • in rinsing the digested sections, prepared for in situ hybridization
  • as a component of solution A to prepare TA-complement haemolysis buffer (TA-CHB)

Biochem/physiol Actions

Triethanolamine hydrochloride acts as a surfactant or pH adjuster. It is also used as an emulsifier in cosmetics and several topical medications.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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25G
Pack Size/Quantity

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Safety assessment of triethanolamine and triethanolamine-containing ingredients as used in cosmetics
Fiume M, et al.
International Journal of Toxicology, 32(3\_suppl), 59S-83S (2013)
The serum complement system: a simplified laboratory exercise to measure the activity of an important component of the immune system
Inglis JE, et al.
Advances in Physiology Education, 32(4), 317-321 (2008)
Gender difference in hypothalamic-pituitary-adrenal axis response to alcohol in the rat: activational role of gonadal steroids
Ogilvie KM and Rivier C
Brain Research, 766(1-2), 19-28 (1997)
allergic Contact Dermatitis to Triethanolamine in a Child
Milanesi N, et al.
Pediatric Dermatology, 32(3), e112-e113 (2015)
Toxicology of mono-, di-, and triethanolamine
Reviews of Environmental Contamination and Toxicology, 1-86 (1997)

Protocols

Enzymatic Assay of Aprotinin

Objective: To standardize a procedure for the enzymatic assay of Aprotinin.

Enzymatic Assay of Hexokinase

To measure hexokinase activity, a continuous spectrophotometric rate-determination assay is used at 340 nm. Hexokinase catalyzes the phosphorylation of D-hexose sugars using ATP as the phosphate source.

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