Skip to Content
MilliporeSigma

T2501

Sigma-Aldrich

L-Thyroxine sodium salt pentahydrate

synthetic (organic), ≥98% (HPLC), Thyroid hormone, powder

Synonym(s):

3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanine sodium salt, Sodium levothyroxine, T4

Slide 1 of 1
Sign Into View Organizational & Contract Pricing

Select a Size

1 G
$196.00
5 G
$786.00

$196.00

Available to ship TODAYDetails

Request a Bulk Order

About This Item

Linear Formula:
HOC6H2I2OC6H2I2CH2CH(NH2)COONa · 5H2O
CAS Number:
6106-07-6
Molecular Weight:
888.93
Beilstein/REAXYS Number:
5721845
EC Number:
200-221-4
MDL number:
MFCD00149110
UNSPSC Code:
51111800
PubChem Substance ID:
24900041
NACRES:
NA.32
Biological source:
synthetic (organic)
Form:
powder
Assay:
≥98% (HPLC)

Key Documents

View All Documentation

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

L-Thyroxine sodium salt pentahydrate, ≥98% (HPLC), powder

biological source

synthetic (organic)

Quality Level

200

sterility

non-sterile

assay

≥98% (HPLC)

form

powder

mp

207-210 (dec.) (lit.)

solubility

4 M NH4OH in methanol: 50 mg/mL, clear to hazy, colorless to yellow

shipped in

ambient

storage temp.

−20°C

SMILES string

O.O.O.O.O.[Na+].N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C([O-])=O

InChI

1S/C15H11I4NO4.Na.5H2O/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;;;;;;/h1-2,4-5,12,21H,3,20H2,(H,22,23);;5*1H2/q;+1;;;;;/p-1/t12-;;;;;;/m0....../s1

InChI key

JMHCCAYJTTWMCX-QWPJCUCISA-M

Gene Information

mouse ... Cnr2(12802)
rat ... Cnr1(25248)

Looking for similar products? Visit Product Comparison Guide

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
T0397T2376T1775
L-Thyroxine sodium salt pentahydrate ≥98% (HPLC), powder

Sigma-Aldrich

T2501

L-Thyroxine sodium salt pentahydrate

L-Thyroxine sodium salt pentahydrate γ-irradiated, powder, BioXtra, suitable for cell culture

Sigma-Aldrich

T0397

L-Thyroxine sodium salt pentahydrate

L-Thyroxine ≥98% (HPLC)

Sigma-Aldrich

T2376

L-Thyroxine

L-Thyroxine powder, BioReagent, suitable for cell culture

Sigma-Aldrich

T1775

L-Thyroxine

biological source

synthetic (organic)

biological source

synthetic (organic)

biological source

synthetic

biological source

synthetic

assay

≥98% (HPLC)

assay

≥98%

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

powder

form

powder

form

powder

form

powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

room temp

storage temp.

room temp

solubility

4 M NH4OH in methanol: 50 mg/mL, clear to hazy, colorless to yellow

solubility

cell culture medium: 0.1 mg/mL, H2O: soluble

solubility

4 M NH4OH in methanol: 50 mg/mL, clear to hazy, yellow

solubility

4 M NH4OH in methanol: 50 mg/mL, clear to hazy, yellow

Biochem/physiol Actions

L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and thus, protein synthesis.

Preparation Note

L-Thyroxine sodium salt pentahydrate dissolves in 4 N NH4OH in methanol at 50 mg/ml to yield a clear to hazy, colorless to yellow solution.

related product

Product No.
Description
Pricing

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H372

Hazard Classifications

STOT RE 1

target_organs

Thyroid,Cardio-vascular system,Kidney

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCN3101
BCCJ6743
BCCL4029
BCCH2561
BCCG2926

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Giuseppe Ianiri et al.
mBio, 6(2) (2015-04-02)
Fungal diseases represent a major burden to health care globally. As with other pathogenic microbes, there is a limited number of agents suitable for use in treating fungal diseases, and resistance to these agents can develop rapidly. Cryptococcus neoformans is
Mahdokht Jouiaei et al.
Molecular biology and evolution, 32(6), 1598-1610 (2015-03-12)
Despite Cnidaria (sea anemones, corals, jellyfish, and hydroids) being the oldest venomous animal lineage, structure-function relationships, phyletic distributions, and the molecular evolutionary regimes of toxins encoded by these intriguing animals are poorly understood. Hence, we have comprehensively elucidated the phylogenetic
Pelin Sahlén et al.
Genome biology, 16, 156-156 (2015-08-28)
Although the locations of promoters and enhancers have been identified in several cell types, we still have limited information on their connectivity. We developed HiCap, which combines a 4-cutter restriction enzyme Hi-C with sequence capture of promoter regions. Applying the
Naoomi Tominaga et al.
Nature communications, 6, 6716-6716 (2015-04-02)
Brain metastasis is an important cause of mortality in breast cancer patients. A key event during brain metastasis is the migration of cancer cells through blood-brain barrier (BBB). However, the molecular mechanism behind the passage through this natural barrier remains
Tais A P F Doll et al.
Nanomedicine : nanotechnology, biology, and medicine, 11(7), 1705-1713 (2015-06-09)
Successful vaccine development remains a huge challenge for infectious diseases such as malaria, HIV and influenza. As a novel way to present antigenic epitopes to the immune system, we have developed icosahedral self-assembling protein nanoparticles (SAPNs) to serve as a
View All Related Papers

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service