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MilliporeSigma

T4509

Sigma-Aldrich

4-Thiouridine

≥98%

Synonym(s):

4sU, RNA synthesis inhibitor, Thiouridine

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25 MG
$232.00
100 MG
$610.00
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$1,290.00

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25 MG
$232.00
100 MG
$610.00
250 MG
$1,290.00

About This Item

Empirical Formula (Hill Notation):
C9H12N2O5S
CAS Number:
13957-31-8
Molecular Weight:
260.27
EC Number:
237-735-3
MDL number:
MFCD00006538
UNSPSC Code:
41106305
PubChem Substance ID:
24900212
NACRES:
NA.51

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$232.00

In StockDetails

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biological source

synthetic (organic)

Quality Level

200

assay

≥98%

form

powder

solubility

water: 20 mg/mL, clear

storage temp.

−20°C

SMILES string

OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=S)NC2=O

InChI

1S/C9H12N2O5S/c12-3-4-6(13)7(14)8(16-4)11-2-1-5(17)10-9(11)15/h1-2,4,6-8,12-14H,3H2,(H,10,15,17)/t4-,6-,7-,8-/m1/s1

InChI key

ZLOIGESWDJYCTF-XVFCMESISA-N

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1 of 4

This Item
L9504400046R4752
4-Thiouridine ≥98%

T4509

4-Thiouridine

D-Luciferin synthetic

L9504

D-Luciferin

Hydroxyurea Anti-neoplastic agent that blocks DNA replication by inhibiting ribonucleotide reductase.

400046

Hydroxyurea

Sigma-Aldrich

R4752

Ribonucleic acid, transfer from bovine liver

biological source

synthetic (organic)

biological source

synthetic

biological source

-

biological source

-

Quality Level

200

Quality Level

300

Quality Level

100

Quality Level

200

assay

≥98%

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

-

form

powder

form

powder

form

solid

form

lyophilized powder

solubility

water: 20 mg/mL, clear

solubility

DMSO: 10 mg/mL, clear, colorless to faintly yellow

solubility

water: 5 mg/mL

solubility

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

General description

4-Thiouridine is a photoreactive uridine analog.[1]

Application

4-Thiouridine has been used in labeling and isolation of nascent RNAs.[2][3][4]

Biochem/physiol Actions

4-Thiouridine plays a role in assessing nascent RNA synthesis.[5] It also enhances site-specific crosslinking. 4-Thiouridine also acts as a photoaffinity probe due to its stability even while lacking specific photoactivation. It can also be incorporated into RNAs.[6]

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000460370
0000460370
0000460369
0000460367
0000460367

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