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T4509

4-Thiouridine

≥98%, synthetic (organic), powder

Synonym(s):

4sU, RNA synthesis inhibitor, Thiouridine

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Size/SKUAvailabilityPrice
25 mg

Available to ship TODAYfromMILWAUKEE

$248.00
100 mg

Available to ship TODAYfromMILWAUKEE

$653.00
250 mg

Available to ship TODAYfromMILWAUKEE

$1,380.00

About This Item

Empirical Formula (Hill Notation):
C9H12N2O5S
CAS Number:
Molecular Weight:
260.27
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
237-735-3
MDL number:
Assay:
≥98%
Biological source:
synthetic (organic)
Form:
powder
Solubility:
water: 20 mg/mL, clear
Storage temp.:
−20°C

$248.00


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Product Name

4-Thiouridine, ≥98%

biological source

synthetic (organic)

Quality Segment

assay

≥98%

form

powder

solubility

water: 20 mg/mL, clear

storage temp.

−20°C

SMILES string

OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=S)NC2=O

InChI

1S/C9H12N2O5S/c12-3-4-6(13)7(14)8(16-4)11-2-1-5(17)10-9(11)15/h1-2,4,6-8,12-14H,3H2,(H,10,15,17)/t4-,6-,7-,8-/m1/s1

InChI key

ZLOIGESWDJYCTF-XVFCMESISA-N

General description

4-Thiouridine is a photoreactive uridine analog.[1]

Application

4-Thiouridine has been used in labeling and isolation of nascent RNAs.[2][3][4]

Biochem/physiol Actions

4-Thiouridine plays a role in assessing nascent RNA synthesis.[5] It also enhances site-specific crosslinking. 4-Thiouridine also acts as a photoaffinity probe due to its stability even while lacking specific photoactivation. It can also be incorporated into RNAs.[6]

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This Item
L9504400046R4752
description

≥98%

description

synthetic

description

Anti-neoplastic agent that blocks DNA replication by inhibiting ribonucleotide reductase.

description

Type XI, lyophilized powder

biological source

synthetic (organic)

biological source

synthetic

biological source

-

biological source

-

Quality Level

200

Quality Level

300

Quality Level

100

Quality Level

200

form

powder

form

powder

form

solid

form

lyophilized powder

assay

≥98%

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

solubility

water: 20 mg/mL, clear

solubility

DMSO: 10 mg/mL, clear, colorless to faintly yellow

solubility

water: 5 mg/mL

solubility

-


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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