Transforming Growth Factor-β Soluble Receptor III human

>97% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

MDL number:
Pricing and availability is not currently available.

biological source



expressed in NSO cells


>97% (SDS-PAGE)


lyophilized powder

mol wt

100 kDa by SDS-PAGE (glycosylation)
predicted mol wt 84 kDa


pkg of 1 mg

storage condition

avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)


endotoxin, tested

UniProt accession no.

storage temp.


Gene Information

human ... TGFBR3(7049)


Transforming Growth Factor-β soluble receptor III human can be used to study TGF-β- mediated signal tranduction.

Biochem/physiol Actions

Transforming Growth Factor-β soluble receptor III human also known as betaglycan facilitates as an inhibin co-receptor with ActRII and mediates functional antagonism of activin signalling.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 5 mg bovine serum albumin

Analysis Note

The receptor-mediated activity is measured by its ability to inhibit the TGF-β2 bioactivity in HT-2 cells.


NONH for all modes of transport

WGK Germany


Certificate of Analysis
Certificate of Origin
M L Tsang et al.
Cytokine, 7(5), 389-397 (1995-07-01)
Recombinant human transforming growth factor soluble receptor Type II (rhTGF-beta sRII) corresponding to the 159 amino acid extracellular domain of hTGF-beta RII has been expressed in insect cells using the baculovirus expression system or in a mouse myeloma cell line....
K A Lewis et al.
Nature, 404(6776), 411-414 (2000-04-04)
Activins and inhibins, structurally related members of the TGF-beta superfamily of growth and differentiation factors, are mutually antagonistic regulators of reproductive and other functions. Activins bind specific type II receptor serine kinases (ActRII or IIB) to promote the recruitment and...
There are five identified glycosaminoglycan chains (see Figure 1): Hyaluronan is not sulfated, but the other glycosaminoglycan chains contain sulfate substituents at various positions of the chain.
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Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units.
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