T5316

Sigma-Aldrich

TAPS

BioPerformance Certified, suitable for cell culture, ≥99.5% (titration)

Synonym(s):
[(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]-1-propanesulfonic acid, N-[Tris(hydroxymethyl)methyl]-3-aminopropanesulfonic acid
Empirical Formula (Hill Notation):
C7H17NO6S
CAS Number:
Molecular Weight:
243.28
Beilstein/REAXYS Number:
2452420
EC Number:
MDL number:
PubChem Substance ID:
Pricing and availability is not currently available.

grade

BioPerformance Certified

Quality Level

assay

≥99.5% (titration)

form

crystalline powder

application(s)

cell culture | mammalian: suitable

useful pH range

7.7 - 9.1

pKa 

8.4

mp

230-235 °C (dec.)

solubility

water: 0.5 g/mL, clear, colorless

cation traces

heavy metals (as Pb): ≤5 ppm

Featured Industry

Diagnostic Assay Manufacturing

foreign activity

DNase, RNase, protease, none detected

SMILES string

OCC(CO)(CO)NCCCS(O)(=O)=O

InChI

1S/C7H17NO6S/c9-4-7(5-10,6-11)8-2-1-3-15(12,13)14/h8-11H,1-6H2,(H,12,13,14)

InChI key

YNLCVAQJIKOXER-UHFFFAOYSA-N

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Flash Point(F)

230.0 °F - closed cup

Flash Point(C)

> 110 °C - closed cup

Z Zeng et al.
Analytical biochemistry, 252(1), 110-114 (1997-11-05)
High-resolution capillary electrophoresis sizing of preformed complexes of bis-intercalating fluorescent dyes with double-stranded DNA has been demonstrated using hydroxyethylcellulose and 3-[tris-(hydroxymethyl) methylamino]-1-propanesulfonic acid-tetrapentylammonium (Taps-NPe+4) buffers (S. M. Clark and R. A. Mathies, Anal. Chem. 69, 1355-1363, 1997). Such capillary electrophoresis...
Seung-ick Oh et al.
TheScientificWorldJournal, 2014, 957548-957548 (2014-07-06)
Somatic cells were directly converted to functional neurons through the use of a combination of transcription factors, including Ascl1, Brn2, and Myt1l. However, a major limitation is the lack of a reliable source of cell-replacement therapy for neurological diseases. Here...
D Liang et al.
Electrophoresis, 21(17), 3600-3608 (2001-03-29)
A new method to introduce the concentration gradient into the capillary has been developed and its application to DNA capillary electrophoresis is presented. The concentration gradient produced by mixing 5% w/v polyacrylamide-co-poly(N-dimethylacrylamide) (PAM-co-PDMA) solution and 1 x Tris/N-tris(hydroxymethyl)methyl-3-amino-propanesulfonic acid/EDTA (TT)...
Patrick Kwan et al.
Journal of the American Chemical Society, 137(42), 13556-13565 (2015-10-06)
We report the first direct electrochemical characterization of the impact of oxygen on the hydrogen oxidation activity of an oxygen-tolerant, group 3, soluble [NiFe]-hydrogenase: hydrogenase I from Pyrococcus furiosus (PfSHI), which grows optimally near 100 °C. Chronoamperometric experiments were used...
John-Paul Bacik et al.
The Journal of biological chemistry, 290(44), 26638-26648 (2015-09-12)
The most abundant carbohydrate product of cellulosic biomass pyrolysis is the anhydrosugar levoglucosan (1,6-anhydro-β-d-glucopyranose), which can be converted to glucose 6-phosphate by levoglucosan kinase (LGK). In addition to the canonical kinase phosphotransfer reaction, the conversion requires cleavage of the 1,6-anhydro...

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