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T6023

Sigma-Aldrich

(±)-Thiopental sodium salt sodium carbonate mixture

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Synonym(s):
5-Ethyl-5-(1-methylbutyl)-2-thiobarbituric acid, Pentothal
Empirical Formula (Hill Notation):
C11H17N2NaO2S
CAS Number:
Molecular Weight:
264.32
EC Number:
PubChem Substance ID:

composition

Thiopental sodium, ~91% (remainder is sodium carbonate)

drug control

USDEA Schedule III; regulated under CDSA - not available from Sigma-Aldrich Canada

solubility

H2O: >10 mg/mL
alcohol: soluble

SMILES string

[Na].[Na+].[Na+].[O-]C([O-])=O.CCCC(C)C1(CC)C(=O)NC(=S)NC1=O

Biochem/physiol Actions

Intravenous anesthetic

pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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Y F Huang et al.
Journal of pharmaceutical sciences, 87(7), 854-858 (1998-07-02)
Previous reports have suggested that tachycardia alone can increase the rate of myocardial uptake of some drugs. As part of a systematic study of the determinants of the myocardial uptake and effects of drugs in critical illness, the effect of
H Qu et al.
Biochemical pharmacology, 58(6), 1075-1080 (1999-10-06)
The effect of thiopental on glutamate metabolism was studied by 13C magnetic resonance spectroscopy. Cerebral cortical astrocytes were incubated with 0.5 mM [U-13C]glutamate for 2 hr in the presence of 0.5 or 1 mM thiopental. Labeled glutamate, glutamine, aspartate, and

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