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T8691

Sigma-Aldrich

Taurine

suitable for cell culture, meets USP testing specifications

Synonym(s):
2-Aminoethanesulfonic acid
Linear Formula:
NH2CH2CH2SO3H
CAS Number:
Molecular Weight:
125.15
Beilstein:
1751215
EC Number:
MDL number:
PubChem Substance ID:

Quality Level

Agency/Method

meets USP testing specifications

product line

BioXtra

form

crystalline powder

application(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white

mp

>300 °C (lit.)

SMILES string

NCCS(O)(=O)=O

InChI

1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)

InChI key

XOAAWQZATWQOTB-UHFFFAOYSA-N

Gene Information

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Application

Taurine has been used:
  • as a component of cardiomyocyte dissociation solution
  • as a supplement for modified synthetic oviduct fluid (m-SOF) medium to culture the presumptive zygotes
  • as a constituent of low Ca2+ solution employed in preparation of collagenase B solution for colony dissociation into single cells
  • to assess its effect on development of bovine embryos fertilized with different bull semen during in vitro fertilization
  • as a component of culture media for derivation of cornea organoids

Packaging

25, 100 g in poly bottle
1 kg in poly bottle

Biochem/physiol Actions

Non-selective endogenous agonist at glycine receptors. Conditionally essential sulfonated amino acid which modulates apoptosis in some cells; functions in many metabolic activities; a product of methionine and cysteine metabolism.
Taurine is predominantly found in the retina and heart and is also found in the brain, intestine, skeletal muscles and kidneys. It controls the concentration of intracellular calcium, protects against ischemia-reperfusion injury and possesses blood pressure-lowering properties. Taurine also plays a vital role in bile formation and fat digestion. Deficiency of taurine is associated with development of anxiety, hyperactivity, epilepsy and depression.

Storage Class Code

13 - Non Combustible Solids

WGK Germany

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Patient-specific induced pluripotent stem cell models: generation and characterization of cardiac cells
Zanella F and Sheikh F
Methods in Molecular Biology, 147-162 (2014)
The Effect of Various Concentrations of Taurine during In vitro Fertilization on the Development of Bovine Embryos Fertilized with Spermatozoa from Three Different Bulls
Tsuzuki Y, et al.
Asian-Australasian Journal of Animal Sciences (2010)
Variations in bovine embryo production between individual donors for OPU-IVF are closely related to glutathione concentrations in oocytes during in vitro maturation
Hidaka T, et al.
Theriogenology, 113(2), 176-182 (2018)
Scalable expansion of human pluripotent stem cells in suspension culture
Zweigerdt R, et al.
Nature Protocols, 6(5), 689-689 (2011)
Cornea organoids from human induced pluripotent stem cells
Foster JW, et al.
Scientific Reports, 7 (2017)

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