T8877 is tested for solubility at 50 mg/ml in water. Although no suitability testing is performed, 2,3,5-Triphenyltetrazolium chloride (Tetrazolium Red) is often used to assess plant viability using a 10 mg/ml solution. Other uses, such as staining brain or heart tissue, have been reported.
T8877
2,3,5-Triphenyltetrazolium chloride
≥98.0% (HPLC)
2,3,5-Triphenyltetrazolium chloride
1 of 2 reviewers took part in a promotion
Synonym(s):
TPTZ, TTZ, Tetrazolium Red
Sign In to View Organizational & Contract Pricing.
Select a Size
5 G
$65.50
10 G
$96.60
25 G
$171.00
50 G
$279.00
100 G
$479.00
About This Item
Empirical Formula (Hill Notation):
C19H15ClN4
CAS Number:
Molecular Weight:
334.80
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
EC Number:
206-071-6
Beilstein/REAXYS Number:
3923356
MDL number:
Skip To
Product Name
2,3,5-Triphenyltetrazolium chloride, ≥98.0% (HPLC)
InChI key
PKDBCJSWQUOKDO-UHFFFAOYSA-M
InChI
1S/C19H15N4.ClH/c1-4-10-16(11-5-1)19-20-22(17-12-6-2-7-13-17)23(21-19)18-14-8-3-9-15-18;/h1-15H;1H/q+1;/p-1
SMILES string
[Cl-].c1ccc(cc1)-c2nn(-c3ccccc3)[n+](n2)-c4ccccc4
assay
≥98.0% (HPLC)
form
powder
color
faintly yellow
solubility
H2O: 50 mg/mL
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
2-8°C
Quality Level
Looking for similar products? Visit Product Comparison Guide
1 of 4
This Item | 294438 | S4131 | N7005 |
|---|---|---|---|
| form powder | form powder | form powder | form powder |
| application(s) diagnostic assay manufacturing | application(s) diagnostic assay manufacturing | application(s) diagnostic assay manufacturing | application(s) diagnostic assay manufacturing |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. room temp | storage temp. 2-8°C |
| solubility H2O: 50 mg/mL | solubility acetonitrile: 50 mg/mL | solubility chloroform: 1 mg/mL, clear, red | solubility water: 10 mg/mL, dark red |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| assay ≥98.0% (HPLC) | assay 97% | assay - | assay - |
Application
General description
2,3,5-Triphenyltetrazolium chloride is a colorless water-soluble dye. In the mitochondria of living cells, it is reduced to a deep red, water-insoluble compound (formazan). 2,3,5-Triphenyltetrazolium chloride helps to distinguish between viable and infarcted brain tissue after stroke.[3]
related product
Product No.
Description
Pricing
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Flam. Sol. 1 - Skin Irrit. 2
Storage Class
4.1B - Flammable solid hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Mannitol-facilitated perfusion staining with 2,3,5-triphenyltetrazolium chloride (TTC) for detection of experimental cerebral infarction and biochemical analysis.
Sun YY et al.
Journal of Neuroscience Methods, 203, 122-122 (2012)
Chesarahmia Dojo Soeandy et al.
Apoptosis : an international journal on programmed cell death, 24(7-8), 578-595 (2019-05-11)
Over the past 30 years a number of animal models of cerebral ischemic injury have been developed. Middle cerebral artery occlusion (MCAO) in particular reproduces both ischemic and reperfusion elements and is widely utilized as a model of ischemic stroke in
Human umbilical mesenchymal stem cells promote recovery after ischemic stroke.
Lin YC et al.
Stroke, 42, 2045-2045 (2011)
Evaluation of a novel epicardial atrial fibrillation treatment system.
Kiser AC et al.
The Annals of Thoracic Surgery, 85, 300-300 (2008)
Jia Huang et al.
Journal of molecular and cellular cardiology, 134, 107-118 (2019-07-14)
Myocardial ischemia/reperfusion (I/R) injury is the major limitation for the cardioprotective action of revascularization after myocardial infarction. Lymphocyte adapter protein (Lnk), an adapter protein, has a regulatory role in multiple signaling pathways by functioning as a scaffold for different substrates.
-
Hello, I wasn’t able to find the recommended proportion of product to water. Could you let me know what ratio I should use? Also, should I be using distilled water? Thank you!
1 answer-
Helpful?
-
-
Bonjour, après avoir reconstitué la poudre dans de l'eau stérile, combien de temps pouvons-nous conserver la préparation au réfrigérateur ? Merci
1 answer-
The long-term solution stability of this product has not been determined. However, product 17779, a sterile 1% solution, has a shelf life of approximately 3 years. Provided that the solution is filter sterilized and stored properly at 2-8°C, a similar shelf life would be expected. Please see the link below to review this product:
https://www.sigmaaldrich.com/product/sial/17779Helpful?
-
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service