T8941

Sigma-Aldrich

L-Tryptophan

from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 99.0-101.0%

Synonym(s):
L-α-Amino-3-indolepropionic acid, (S)-2-Amino-3-(3-indolyl)propionic acid
Empirical Formula (Hill Notation):
C11H12N2O2
CAS Number:
Molecular Weight:
204.23
Beilstein/REAXYS Number:
86197
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26
Pricing and availability is not currently available.

Quality Level

biological source

non-animal source

Agency/Method

USP/NF
meets EP testing specifications
meets JP testing specifications
meets USP testing specifications

product line

BioXtra

assay

99.0-101.0%

form

powder

quality

meets EP, JP, USP testing specifications

application(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white to yellow

mp

280-285 °C (dec.) (lit.)

solubility

1 M HCl: 10 mg/mL

Featured Industry

Pharmaceutical (small molecule)

SMILES string

N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O

InChI

1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1

InChI key

QIVBCDIJIAJPQS-VIFPVBQESA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

L-Tryptophan has been used in PreC media preparation and in cell culture.

Packaging

10 mg in glass bottle
25, 100 g in poly bottle
1 kg in poly bottle

Biochem/physiol Actions

Tryptophan (Trp) is one of the functional amino acids that is associated with growth, reproduction, maintenance and immunity. Increased Trp availability is necessary for the regulation of mood, cognition and behaviour. It is hypothesised that L-Trp might be useful in inducing sleep in healthy adults against the normal circadian rhythm. Trp uptake by the brain depends on the plasma ratio of Trp to all of the other LNAAs (large neutral amino acids). Higher the Trp:LNAAs ratio, greater is the Trp uptake.

Other Notes

Amino acid precursor of serotonin and melatonin

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Preparation of Purified Gram-positive Bacterial Cell Wall and Detection in Placenta and Fetal Tissues
Beth Mann
Bio-protocol, 6(23) (2016)
Amino acids: metabolism, functions, and nutrition
Amino Acids (2009)
Nutrient supplements boost yeast
transformation efficiency
Sheng-ChunYu
Scientific Reports (2016)
Effects of tryptophan loading on human cognition, mood, and sleep
B.Y. Silber and J.A.J. Schmitt
Neuroscience and Biobehavioral Reviews, 34(3), 387-407 (2010)
Kei Hiruma et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(23), 9589-9594 (2013-05-23)
The hypersensitive response (HR) is a type of strong immune response found in plants that is accompanied by localized cell death. However, it is unclear how HR can block a broad range of pathogens with different infective modes. In this...

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service

Social Media

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

MilliporeSigma

Research. Development. Production.

We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.

Reproduction of any materials from the site is strictly forbidden without permission.