The vial content for this product is determined on a lot-specific basis and is reported on the Certificate of Analysis. The minimum protein content will be 35 mg/vial. A brief review of recent lots shows the average of 39 mg/vial. See the links below to review several recent Certificates:
https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/T9145-1VL0000255415.pdf
https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/T9145-1VL-KCSLCN3202.pdf
https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/T9145-1VLSLCM4718.pdf
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 vial | Available to ship TODAYfromMILWAUKEE | $150.00 |
About This Item
Form:
powder
Biological source:
bovine thyroid
Mol wt:
~670 kDa
$150.00
Available to ship TODAYDetails
biological source
bovine thyroid
Quality Level
form
powder
mol wt
~670 kDa
technique(s)
bioconjugation: suitable
UniProt accession no.
storage temp.
−20°C
Gene Information
cow ... TG(280706)
Application
Often used as a carrier protein for the production of antibodies. Its advantage is the large number of tyrosine residues that can be used for conjugation using the diazo reaction.
Thyroglobulin is used for antibody purification and characterization. Thyroglobulin has been used in studies assessing the monitoring of differentiated thyroid cancer as well as to develop an accurate diagnostic tool for patients with autoimmune thyroid diseases.
Biochem/physiol Actions
Iodine-containing protein that is stored in the thyroid gland. Converted into circulating thyroxines when the thyroid is stimulated by thyroid-stimulating hormone (TSH) from the pituitary. Because its expression is unique to the thyroid, it is a sensitive indicator of recurrence or metastasis of thyroid cancer that has been treated by thyroid ablation.
1 of 1
This Item | |||
|---|---|---|---|
| biological source bovine thyroid | biological source bovine thyroid | biological source human thyroid | biological source - |
| technique(s) bioconjugation: suitable | technique(s) - | technique(s) - | technique(s) liquid chromatography (LC): suitable |
| form powder | form powder | form lyophilized | form liquid |
| mol wt ~670 kDa | mol wt ~670 kDa | mol wt - | mol wt 302607 Da |
| Gene Information cow ... TG(280706) | Gene Information cow ... TG(280706) | Gene Information - | Gene Information - |
| storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. −20°C |
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Related Content
Perrine Munier et al.
Annales de biologie clinique, 69(6), 721-725 (2011-11-30)
Thyroglobuline (Tg) is a large molecule of high molecular weight mainly indicated in monitoring differentiated thyroid cancer (DTC), its measurement remains difficult. We report the case of a patient who underwent total thyroidectomy for a poorly differentiated thyroid insular carcinoma.
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| T9145-1VL | 04061833296899 |
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Hello. Please, could you tell me the weight of powder in 1 vial of the product with catalog number T9145 (Thyroglobulin from bovine thyroid, 1VL). Thanks
1 answer-
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