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Key Documents

UC205

Sigma-Aldrich

Dextrorphan

Synonym(s):

(+)-3-Hydroxy-17-methylmorphinan, 1,3,4,9,10,10a-Hexahydro-6-hydroxy-2H-10,4a-(iminoethano)-11-methylphenanthrene

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5 MG
$754.00
10 MG
$1,310.00

About This Item

Empirical Formula (Hill Notation):
C17H23NO
CAS Number:
Molecular Weight:
257.37
EC Number:
MDL number:
UNSPSC Code:
12161501
PubChem Substance ID:
NACRES:
NA.77

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form

solid

optical activity

[α]/D ≥+54°

color

white to off-white

mp

≥195 °C

solubility

saline: soluble(lit.)

storage temp.

2-8°C

SMILES string

CN1CC[C@@]23CCCC[C@@H]2[C@@H]1Cc4ccc(O)cc34

InChI

1S/C17H23NO/c1-18-9-8-17-7-3-2-4-14(17)16(18)10-12-5-6-13(19)11-15(12)17/h5-6,11,14,16,19H,2-4,7-10H2,1H3/t14-,16+,17+/m1/s1

InChI key

JAQUASYNZVUNQP-PVAVHDDUSA-N

Gene Information

human ... GRIN2A(2903)
rat ... Grin2a(24409)

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This Item
SML1468L5143D127
form

solid

form

powder

form

powder

form

powder

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

-

solubility

saline: soluble(lit.)

solubility

DMSO: 5 mg/mL, clear (warmed)

solubility

H2O: >20 mg/mL

solubility

H2O: >10 mg/mL

color

white to off-white

color

white to beige

color

white

color

white

optical activity

[α]/D ≥+54°

optical activity

[α]/D -305 to -325°, c = 1 in dichloromethane

optical activity

-

optical activity

-

Application

CYP2D6 O-Demethyl metabolite of dextromethorphan
Dextrorphan has been studies as an N-methyl-D-aspartate (NMDA) receptor antagonist in Xenopus oocytes and hippocampal neuron cultures[1].

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Preparation Note

Dextrorphan is soluble in water[1].

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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