V5255
Anti-Vimentin Antibody
mouse monoclonal, VIM-13.2
Synonym(s):
Anti-F5H288
Sign Into View Organizational & Contract Pricing
Select a Size
100 μL
$443.76
0.2 ML
$712.00
$443.76
List Price$516.00Save 14%Web-Only Promotion
Available to ship onMay 20, 2025Details
Request a Bulk Order
All Photos(5)
Select a Size
Change View
100 μL
$443.76
0.2 ML
$712.00
About This Item
$443.76
List Price$516.00Save 14%Web-Only Promotion
Available to ship onMay 20, 2025Details
Request a Bulk Order
Recommended Products
Product Name
Monoclonal Anti-Vimentin antibody produced in mouse, clone VIM-13.2, ascites fluid
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
VIM-13.2, monoclonal
species reactivity
chicken, rat, human, rabbit, frog, mouse
technique(s)
indirect immunofluorescence: 1:200 using cultured chicken fibroblasts
western blot: 1:500 using human fibroblasts cell extract
isotype
IgM
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... VIM(7431)
mouse ... Vim(22352)
rat ... Vim(81818)
General description
Vimentin is a 53 kD type III intermediate filaments expressed in breast myoepithelial cells, osteocytes, langerhans cells of the skin, schwann cells and astrocytes. Monoclonal anti-vimentin antibody can be used in immunofluorescent labeling of frozen tissue sections to localize vimentin in fibroblasts, endothelial cells, lymphoid tissues and melanocytes. It can also be used in western blotting. Mouse anti-vimentin antibody reacts specifically with vimentin. This product has also shown best reactivity with cultured chicken fibroblasts and can also react with human and mouse cells or tissues.The protein monomers consist of α-helical rod, flanked by head and tail domains. The VIM gene is mapped to human chromosome 10p13.
Immunogen
human foreskin fibroblasts
Application
Monoclonal anti-vimentin antibody can be used in the following:
- Immunocytochemical localization of vimentin in normal and pathological tissue of mesenchymal origin.
- It can also be used in immunoblotting
- Immunofluorescence
- Further, anti-vimentin antibody can be used to distinguish tumors and metastatic lesions derived from sarcomas, lymphomas, and melanomas.
Biochem/physiol Actions
Vimentin has a crucial role in maintaining cell shape and motility. It also provides mechanical stress tolerance for mesenchymal cells. Vimentin induces fibroblast motility and promotes wound healing process. Vimentin filaments form a part of cytoskeleton filament system and therefore, support and secure the cell organelles and also maintain cellular integrity. Vimentin is associated with the process of initiation, progression, metastasis and epithelial-mesenchymal transition of cancer cells, thereby contributing to tumorigenesis. Upregulation of this gene is observed in various cancers including prostate cancer, gastrointestinal tumors, lung cancer, breast cancer, CNS tumors and malignant melanoma.
Other Notes
This product can be found as purified product that was produced using cell culture hybridoma product.
SAB4200716 Anti-Vimentin antibody, Mouse monoclonal
clone VIM-13.2, purified from hybridoma cell culture
SAB4200716 Anti-Vimentin antibody, Mouse monoclonal
clone VIM-13.2, purified from hybridoma cell culture
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Not finding the right product?
Try our Product Selector Tool.
related product
Product No.
Description
Pricing
Storage Class
10 - Combustible liquids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Lot/Batch Number
Don't see the Right Version?
If you require a particular version, you can look up a specific certificate by the Lot or Batch number.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
Lung cancer exosomes as drivers of epithelial mesenchymal transition.
Rahman M A, et al.
Oncotarget, 7(34), 54852-54852 (2016)
Yvonne Ting-Chun Yu et al.
Journal of biomedical science, 23, 14-14 (2016-01-24)
Severe acute respiratory syndrome coronavirus (SARS-CoV) caused a global panic due to its high morbidity and mortality during 2002 and 2003. Soon after the deadly disease outbreak, the angiotensin-converting enzyme 2 (ACE2) was identified as a functional cellular receptor in
A novel role of vimentin filaments; binding and stabilization of collagen mRNAs.
Challa A A and Stefanovic B
Molecular and Cellular Biology (2011)
Qing Wang et al.
BMC cancer, 13, 137-137 (2013-03-22)
We attempted to identify novel biomarkers and therapeutic targets for esophageal squamous cell carcinoma by gene expression profiling of frozen esophageal squamous carcinoma specimens and examined the functional relevance of a newly discovered marker gene, WDR66. Laser capture microdissection technique
Downregulation of vimentin expression increased drug resistance in ovarian cancer cells.
Huo Y, et al.
Oncotarget, 7(29), 45876-45876 (2016)
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service
