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X4002

Xanthine

≥99%, synthetic (organic), powder

Synonym(s):

2,6-Dihydroxypurine

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$94.70

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$201.00

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$676.00

$94.70

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About This Item

Empirical Formula (Hill Notation):
C5H4N4O2
CAS Number:
69-89-6
Molecular Weight:
152.11
NACRES:
NA.51
PubChem Substance ID:
24902144
UNSPSC Code:
41106305
EC Number:
200-718-6
MDL number:
MFCD00078453
Beilstein/REAXYS Number:
8733
Assay:
≥99%
Biological source:
synthetic (organic)
Form:
powder
Solubility:
1 M NaOH: 0.1 M, clear, colorless to light yellow

Key Documents

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Product Name

Xanthine, BioUltra, ≥99%

InChI key

LRFVTYWOQMYALW-UHFFFAOYSA-N

InChI

1S/C5H4N4O2/c10-4-2-3(7-1-6-2)8-5(11)9-4/h1H,(H3,6,7,8,9,10,11)

SMILES string

O=C1NC(=O)c2nc[nH]c2N1

biological source

synthetic (organic)

product line

BioUltra

assay

≥99%

form

powder

impurities

≤0.0005% Phosphorus (P), ≤0.1% Insoluble matter

ign. residue

≤0.1%

solubility

1 M NaOH: 0.1 M, clear, colorless to light yellow

anion traces

sulfate (SO42-): <0.05%

cation traces

Al: ≤0.0005%, Ca: ≤0.0005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Mg: ≤0.0005%, NH4+: ≤0.05%, Na: ≤0.005%, Pb: ≤0.001%, Zn: ≤0.0005%

Quality Level

200

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Show Differences

1 of 4

This Item
X0626X7375PHR3262
Xanthine BioUltra, &#8805;99%

Sigma-Aldrich

X4002

Xanthine

Xanthine &#8805;99.5% (HPLC), purified by recrystallization

Sigma-Aldrich

X0626

Xanthine

Xanthine &#8805;99%

Sigma-Aldrich

X7375

Xanthine

Xanthone pharmaceutical secondary standard, certified reference material

Supelco

PHR3262

Xanthone

biological source

synthetic (organic)

biological source

-

biological source

synthetic (organic)

biological source

-

Quality Level

200

Quality Level

400

Quality Level

300

Quality Level

300

assay

≥99%

assay

≥99.5% (HPLC)

assay

≥99%

assay

-

form

powder

form

powder

form

powder

form

-

solubility

1 M NaOH: 0.1 M, clear, colorless to light yellow

solubility

1 M NaOH: soluble 50 mg/mL, clear, colorless to faintly yellow

solubility

1 M NaOH: soluble 50 mg/mL, clear to slightly hazy, NH4OH: freely soluble, NaOH: freely soluble

solubility

-

impurities

≤0.0005% Phosphorus (P), ≤0.1% Insoluble matter

impurities

-

impurities

-

impurities

-

General description

Xanthine is a purine that can be produced in the purine metabolic pathway via different precursors:
  • Guanine deamination by guanine deaminase
  • Hypoxanthine conversion by xanthine oxidoreductase
Xanthine or its derivatives are naturally present in animal organs, yeast, potatoes, coffee beans, and tea.

Application

Xanthine has been used as a substrate for the determination of xanthine oxidase (XOD) inhibitory activity. It has also been used in the following systems:
  • yeast culture[1]
  • human cell line culture
  • recombinant viruses cloned as bacterial artificial chromosomes in Escherichia coli

Biochem/physiol Actions

Xanthine and xanthine oxidase are used to generate superoxide radicals to measure the activity of superoxide dismutase.

Features and Benefits

  • Tested for trace metal content (fuller details in Properties section and on Specification Sheet)
  • Tested for trace sulfate content (fuller details in Properties section and on Specification Sheet)

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000529050
0000529049
0000529048
0000529050
0000529048

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Raffaello Castoria et al.
Phytopathology, 93(5), 564-572 (2008-10-24)
ABSTRACT We detected the generation of the reactive oxygen species (ROS) superoxide anion ( O.(-) (2)) and hydrogen peroxide (H(2)O(2)) in apple wounds 2 immediately after wounding, and assessed the relationships between (i) timely colonization of apple wounds by biocontrol
Insights from multispectral and molecular docking investigation on the xanthine oxidase inhibition by 1, 4-dicaffeoylquinic acid
Cao W, et al.
Journal of Molecular Structure, 1219, 128475-128475 null
Optimization of total phenolic contents, antioxidant, and in-vitro xanthine oxidase inhibitory activity of sunflower head
Mehmood A, et al.
CYTA-journal of Food, 16, 957-964 null
Avery G Frey et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(22), 8031-8036 (2014-05-21)
Although cells express hundreds of metalloenzymes, the mechanisms by which apoenzymes receive their metal cofactors are largely unknown. Poly(rC)-binding proteins PCBP1 and PCBP2 are multifunctional adaptor proteins that bind iron and deliver it to ferritin for storage or to prolyl
Ken Okamoto et al.
Current pharmaceutical design, 19(14), 2606-2614 (2012-11-03)
Xanthine oxidoreductase (XOR), a complex flavoprotein, catalyzes the metabolic reactions leading from hypoxanthine to xanthine and from xanthine to urate, and both reactions take place at the molybdenum cofactor. The enzyme is a target of drugs for therapy of gout
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