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14022AST

Astec® CHIROBIOTIC® TAG Chiral (5 μm) HPLC Columns

L × I.D. 10 cm × 4.6 mm, HPLC Column

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About This Item

UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52
L × i.d.:
10 cm × 4.6 mm
Particle size:
5 μm
Matrix active group:
teicoplanin aglycone phase
Pore size:
100 Å
Matrix:
High-purity silica gel particle platform, fully porous particle

Key Documents

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Product Name

Astec® CHIROBIOTIC® TAG Chiral HPLC Column, 5 μm particle size, L × I.D. 10 cm × 4.6 mm

material

stainless steel column

agency

suitable for USP L63

description

HPLC column

product line

Astec®

packaging

pkg of 1 ea

manufacturer/tradename

Astec®

parameter

0-45 °C temperature, 241 bar pressure (3500 psi)

technique(s)

HPLC: suitable, LC/MS: suitable

L × I.D.

10 cm × 4.6 mm

matrix

High-purity silica gel particle platform, fully porous particle

matrix active group

teicoplanin aglycone phase

particle size

5 μm

pore size

100 Å

operating pH range

3.0-6.8

separation technique

chiral

Quality Level

100

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This Item
14018AST14019AST14020AST
Astec® CHIROBIOTIC® TAG Chiral HPLC Column 5 μm particle size, L × I.D. 10 cm × 4.6 mm

Supelco

14022AST

Astec® CHIROBIOTIC® TAG Chiral HPLC Column

Astec® CHIROBIOTIC® TAG Chiral HPLC Column 5 μm particle size, L × I.D. 10 cm × 2.1 mm

Supelco

14018AST

Astec® CHIROBIOTIC® TAG Chiral HPLC Column

Astec® CHIROBIOTIC® TAG Chiral HPLC Column 5 μm particle size, L × I.D. 15 cm × 2.1 mm

Supelco

14019AST

Astec® CHIROBIOTIC® TAG Chiral HPLC Column

Astec® CHIROBIOTIC® TAG Chiral HPLC Column 5 μm particle size, L × I.D. 25 cm × 2.1 mm

Supelco

14020AST

Astec® CHIROBIOTIC® TAG Chiral HPLC Column

separation technique

chiral

separation technique

chiral

separation technique

chiral

separation technique

chiral

particle size

5 μm

particle size

5 μm

particle size

5 μm

particle size

5 μm

matrix active group

teicoplanin aglycone phase

matrix active group

teicoplanin aglycone phase

matrix active group

teicoplanin aglycone phase

matrix active group

teicoplanin aglycone phase

L × I.D.

10 cm × 4.6 mm

L × I.D.

10 cm × 2.1 mm

L × I.D.

15 cm × 2.1 mm

L × I.D.

25 cm × 2.1 mm

matrix

High-purity silica gel particle platform, fully porous particle

matrix

High-purity silica gel particle platform, fully porous particle

matrix

High-purity silica gel particle platform, fully porous particle

matrix

High-purity silica gel particle platform, fully porous particle

technique(s)

HPLC: suitable, LC/MS: suitable

technique(s)

HPLC: suitable, LC/MS: suitable

technique(s)

HPLC: suitable, LC/MS: suitable

technique(s)

HPLC: suitable, LC/MS: suitable

General description

The removal of three carbohydrate moieties gives CHIROBIOTIC® TAG complementary selectivity to CHIROBIOTIC® T. Resolution is enhanced toward many of the amino acids, α, β, γ and cyclic, and especially sulfur-containing methionine, histidine and cysteine. A number of neutral molecules like the oxazolidinones, hydantoins and diazepines have shown enhanced resolution and, more remarkably, in the single solvents like methanol, ethanol and acetonitrile. Some acidic molecules have also shown increased selectivity.

  • Bonded phase: Teicoplanin aglycone
  • Operating pH range: 3.0 - 6.8
  • Particle diameter: 5, 10 or 16 μm
  • Pore size: 100 Å

Other Notes

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Legal Information

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC

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Certificates of Analysis (COA)

Lot/Batch Number
299684-01
299683-01
298775-01
298773-01
295824-01

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Abdulrahman A Al-Majed
Journal of pharmaceutical and biomedical analysis, 50(1), 96-99 (2009-05-19)
A direct chiral high-performance liquid chromatography (HPLC) method was developed and validated for the resolution and quantification of antiepileptic drug enantiomers, R-(-)- and S-(+)-vigabatrin (gamma-vinyl-gamma-aminobutyric acid) in pharmaceutical products. The separation was optimized on a macrocyclic glycopeptide antibiotic chiral stationary
Ilaria D'Acquarica et al.
Journal of chromatography. A, 1061(2), 167-173 (2005-01-12)
We describe a new tandem-columns chiral-achiral HPLC arrangement by using a chiral column (CHIROBIOTIC TAG) connected in series with an achiral column (Spherisorb S5 SCX), based on a strong cationic exchange mechanism; this approach is very useful for the analysis
Adsorption behavior of a teicoplanin aglycone bonded stationary phase under harsh overload conditions
Bechtold, Matthias, et al.
Journal of Chromatography A, 1154 (1-2), 2477-2286 (2007)
Markus Fuereder et al.
Journal of chromatography. A, 1236, 123-131 (2012-04-03)
Teicoplanin aglycone-based chromatography columns (Chirobiotic TAG) enable amino acid enantioseparation with aqueous mobile phases, which perfectly accommodates the distinct hydrophilicity of most amino acids. Therefore, this stationary phase constitutes a promising option in particular for preparative-scale separations that require high
Chemoenzymatic preparation of enantiopure l-benzofuranyl- and l-benzo[b]thiophenyl alanines
Podea, Paula Veronica, et al.
Tetrahedron Asymmetry, 19 (4), 500-511 (2008)
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