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Methanolic HCl

0.5 M HCl in methanol (0.5N), for GC derivatization, ampule of 10 × 5 mL

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Synonym(s):
Hydrogen chloride, Hydrochloric acid solution
Empirical Formula (Hill Notation):
HCl
CAS Number:
Molecular Weight:
36.46
UNSPSC Code:
41116105
PubChem Substance ID:

grade

for GC derivatization

reaction suitability

reagent type: derivatization reagent
reaction type: Esterifications

packaging

ampule of 10 × 5 mL

concentration

0.5 M HCl in methanol (0.5N)

storage temp.

2-8°C

InChI

1S/ClH/h1H

InChI key

VEXZGXHMUGYJMC-UHFFFAOYSA-N

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General description

Methanolic HCl (hydrochloric acid in methanol) is particularly useful for preparing methyl esters of volatile (short chain) fatty acids. Fatty acids are esterified by heating them with an anhydrous alcohol (e.g., methanol) in the presence of an acidic catalyst (e.g., HCl) in a sealed vessel at a high temperature for a short time. In the reaction, a fatty acid molecule and an alcohol molecule are joined, with the release of a water molecule. The derivatives can be quickly and easily recovered, quantitatively, from the reaction medium.

Features and Benefits

  • Derivatization of fatty acids, particularly volatile (short chain) fatty acids.

  • Clean reaction (no side reaction) with volatile by-products.

  • Provides clean, fast, quantitative derivatization.

Related product

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - Met. Corr. 1 - STOT SE 1

target_organs

Eyes,Central nervous system

wgk_germany

WGK 2

flash_point_f

51.8 °F

flash_point_c

11 °C


Certificates of Analysis (COA)

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X Qiu et al.
The Journal of biological chemistry, 276(34), 31561-31566 (2001-06-09)
The existence of Delta 4 fatty acid desaturation in the biosynthesis of docosahexanoic acid (DHA) has been questioned over the years. In this report we describe the identification from Thraustochytrium sp. of two cDNAs, Fad4 and Fad5, coding for Delta
Practical Gas Chromatography: A Comprehensive Reference.
Wilder KD and Engewald W.
Science, 613-614 (2014)
Mitochondrial Function, Part B: Mitochondrial Protein Kinases, Protein Phosphatases and Mitochondrial Diseases.
William SA and Murphy AN.
Science, 88-89 (2009)
[Fluid and electrolyte movements through the gastrointestinal membranes: hydrochloric acid formation and intestinal water transport].
D P Mertz
Klinische Wochenschrift, 45(2), 57-68 (1967-01-15)
Vanessa Zambelli et al.
Anesthesia and analgesia, 120(2), 381-388 (2014-12-17)
Because pulmonary endogenous surfactant is altered during acute respiratory distress syndrome, surfactant replacement may improve clinical outcomes. However, trials of surfactant use have had mixed results. We designed this animal model of unilateral (right) lung injury to explore the effect

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