1,2-Dibromo-3-chloropropane solution

certified reference material, 5000 μg/mL in methanol

CAS Number:
EC Number:

Quality Level


certified reference material


ampule of 1 mL


5000 μg/mL in methanol


HPLC: suitable
gas chromatography (GC): suitable

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single component solution

storage temp.




InChI key


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Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Legal Information

TraceCERT is a registered trademark of Sigma-Aldrich Co. LLC


Skull and crossbonesHealth hazard

Signal Word


Precautionary Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves


UN 2872 6.1 / PGIII

WGK Germany


Flash Point(F)

168.8 °F

Flash Point(C)

76 °C

Certificate of Analysis
Certificate of Origin
Jae-Chun Ryu et al.
Mutagenesis, 17(4), 301-307 (2002-07-12)
1,2-Dibromo-3-chloropropane (DBCP), a soil fumigant against nematodes, has been extensively studied for genotoxicity, carcinogenicity and damage to male reproduction-related organs, as a possible endocrine disruptor. However, the precise mechanisms involved in DBCP-induced mutagenesis and carcinogenesis are as yet unknown. Thus...
[Evidence of toxic effect of a chemical on reproduction ignored].
Maria Albin et al.
Lakartidningen, 106(37), 2296-2297 (2009-10-13)
Heather A Clark et al.
Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews, 23(2), 215-260 (2005-11-18)
Dibromochloropropane (1,2-dibromo-3-chloropropane, DBCP), a pesticide used widely for over 20 years to control nematodes on crops, turf and in nurseries, was banned by the United States Environmental Protection Agency (US EPA) in 1977 because of evidence of infertility in men...
Marvin L Meistrich et al.
Toxicological sciences : an official journal of the Society of Toxicology, 76(2), 418-426 (2003-09-30)
The exposure of men to the nematocide dibromochloropropane (DBCP) has caused prolonged oligo- and azoospermia, which occasionally reverses spontaneously. We recently demonstrated that in testes of rats treated with a dose of DBCP sufficient to reduce the percentage of tubules...
S Benoff et al.
Andrologia, 32(4-5), 317-329 (2000-10-06)
Zinc and lead concentrations were measured in seminal plasma from fertile donors, infertile men with varicocoele and men undergoing work-ups for in vitro fertilization. Ejaculated spermatozoa from these subjects were incubated in vitro with various metal ions and/or dibromoethane and...

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