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47168

3,5-Di-tert-butyl-4-hydroxytoluene

analytical standard

Synonym(s):

3,5-Di-tert-butyl-4-hydroxytoluene, E321

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Pack SizeSKUAvailabilityPrice
500 mg

Available to ship onApril 20, 2026fromMILWAUKEE

$28.50

About This Item

CAS Number:
UNSPSC Code:
12164500
PubChem Substance ID:
EC Number:
204-881-4
MDL number:
NACRES:
NA.24

$28.50


Available to ship onApril 20, 2026Details


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grade

analytical standard

CofA

current certificate can be downloaded

packaging

pkg of 500 mg

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

room temp

SMILES string

Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C

InChI

1S/C15H24O/c1-10-8-11(14(2,3)4)13(16)12(9-10)15(5,6)7/h8-9,16H,1-7H3

InChI key

NLZUEZXRPGMBCV-UHFFFAOYSA-N

Gene Information

human ... CAPN1(823)
rat ... Capn1(29153), Nos1(24598)

General description

3,5-Di-tert-4-butylhydroxytoluene belongs to the class of phenolic antioxidants, added to food and other products such as oils, fats and butter oil to prevent rancidity caused by the oxidation of unsaturated fats.

Application

3,5-Di-tert-4-butylhydroxytoluene may be used as an analytical reference standard for the quantification of the analyte in Eucalyptus wood using chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

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This Item
W21840503762B1215000
technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

technique(s)

-

format

neat

format

-

format

-

format

neat

Quality Level

100

Quality Level

300, 400

Quality Level

200

Quality Level

-

grade

analytical standard

grade

FG, Fragrance grade, Kosher

grade

-

grade

pharmaceutical primary standard

storage temp.

room temp

storage temp.

-

storage temp.

-

storage temp.

2-8°C

packaging

pkg of 500 mg

packaging

-

packaging

-

packaging

-


pictograms

Environment

signalword

Warning

hcodes

Storage Class

11 - Combustible Solids

flash_point_f

260.6 °F - open cup

flash_point_c

127 °C - open cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

Hazard Classifications

Aquatic Chronic 1



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Certificates of Analysis (COA)

Lot/Batch Number

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Articles

Identification and quantification of the most common extractables originating from single-use equipment by GC/MS and an Extractables and Leachables Screening Standard.


Supercritical fluid extraction of phenolic compounds from Eucalyptus globulus Labill bark
Santos.O.AS, et al.
Journal of Supercritical Fluids, 71, 71-79 (2012)
Ultra-high performance liquid chromatography coupled to mass spectrometry applied to the identification of valuable phenolic compounds from Eucalyptus wood
Santos.O.AS, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 938, 65-74 (2013)
Alessia Arena et al.
Food chemistry, 396, 133721-133721 (2022-07-24)
Phthalic acid esters (PAEs), known as phthalates, have a variety of industrial applications, mainly related to their ability to increase plastic softness,flexibility, and durability. With regard to toxicological aspects, several studies suggest that phthalates would act as endocrine-disrupting chemicals, and



Global Trade Item Number

SKUGTIN
4716804061838081407

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

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