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47785

(+)-γ-Tocopherol

analytical standard

Synonym(s):

(R,R,R)-γ-Tocopherol, 7,8-Dimethyltocol

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About This Item

Empirical Formula (Hill Notation):
C28H48O2
CAS Number:
Molecular Weight:
416.68
UNSPSC Code:
12164500
E Number:
E308
PubChem Substance ID:
EC Number:
200-201-5
Beilstein/REAXYS Number:
93072
MDL number:
NACRES:
NA.24
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grade

analytical standard

Quality Level

form

solid

CofA

current certificate can be downloaded

packaging

ampule of 25 mg

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

-10 to -25°C

SMILES string

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2cc(O)c(C)c(C)c2O1

InChI

1S/C28H48O2/c1-20(2)11-8-12-21(3)13-9-14-22(4)15-10-17-28(7)18-16-25-19-26(29)23(5)24(6)27(25)30-28/h19-22,29H,8-18H2,1-7H3/t21-,22-,28-/m1/s1

InChI key

QUEDXNHFTDJVIY-DQCZWYHMSA-N

Gene Information

human ... HMGCR(3156)

General description

γ-Tocopherol is a form of fat-soluble vitamin E and shows anti-oxidant, anti-inflammatory, anti-cell proliferative, and anti-cancer properties.

Application

The analytical standard can also be used as follows:
  • Development and validation of a normal-phase high-performance liquid chromatography (NP-HPLC) method, along with fluorescence detection, to simultaneously determine four tocopherols and four lignans in sesame oil samples
  • Simultaneous determination of vitamin A and all four tocopherol isomers in human serum samples by ultra-high performance liquid chromatography (UHPLC) combined with fluorescence detection following their liquid-liquid extraction (LLE)
  • Separation and estimation of four tocopherols and four tocotrienols in pecan nut cultivar samples using non-aqueous reversed-phase high-performance liquid chromatography (NARP-HPLC) coupled with atmospheric pressure chemical ionization-tandem mass spectrometric (APCI-MS/MS) detection
  • Analysis of different cold pressed oil samples to detect and quantify eight tocol- homologs using a chemometrically-assisted optimized high-performance liquid chromatography (HPLC) with fluorescence detection (FLD) based method
  • Multi-residue determination of tocopherols in aromatic peanut oil (APO) and four refined vegetable oils using high-performance liquid chromatography with UV detection to detect adulteration

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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1 of 1

This Item
T1782V-02147783
technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

form

solid

form

liquid

form

liquid

form

liquid

format

neat

format

-

format

single component solution

format

neat

Quality Level

100

Quality Level

200

Quality Level

300

Quality Level

100

grade

analytical standard

grade

-

grade

certified reference material

grade

analytical standard

storage temp.

-10 to -25°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

-10 to -25°C


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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves



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Certificates of Analysis (COA)

Lot/Batch Number

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Protocols

Separation of (±)-α-Tocopherol, analytical standard; Menadione (K3), analytical standard; (+)-γ-Tocopherol, analytical standard; Cholecalciferol (D3), analytical standard

Separation of δ-Tocopherol, analytical standard; Retinyl acetate; (+)-γ-Tocopherol; α-Tocopherol, ≥95.5%; Retinol; Vitamin A (acetate), meets USP testing specifications.

GB method with Ascentis® Express C30 column achieves baseline resolution for Vitamin A and E critical pair.


Guowei Zheng et al.
Plant diversity, 42(1), 44-51 (2020-03-07)
Understanding the responses of crops to elevated atmospheric carbon dioxide concentrations (E[CO2]) is very important in terms of global food supplies. The present study investigates the effects of CO2 enrichment (to 800 μmol mol-1) on the physiology of soybean plants and the
George Gachumi et al.
Molecules (Basel, Switzerland), 26(5) (2021-04-04)
Phytosterols and tocopherols are commonly used in food and pharmaceutical industries for their health benefits. Current analysis methods rely on conventional liquid chromatography, using an analytical column, which can be tedious and time consuming. However, simple, and fast analytical methods
Elia Stahl et al.
Plant physiology, 181(3), 1008-1028 (2019-09-14)
Tocopherols are lipid-soluble antioxidants synthesized in plastids of plants and other photosynthetic organisms. The four known tocopherols, α-, β-, γ-, and δ-tocopherol, differ in number and position of methyl groups on their chromanol head group. In unstressed Arabidopsis (Arabidopsis thaliana)



Global Trade Item Number

SKUGTIN
4778504061838081582

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

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