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MilliporeSigma

47863

Supelco

L-Ascorbic acid

analytical standard

Synonym(s):

L-Threoascorbic acid, Antiscorbutic factor, Vitamin C

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1000 MG
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About This Item

Empirical Formula (Hill Notation):
C6H8O6
CAS Number:
Molecular Weight:
176.12
Beilstein/REAXYS Number:
84272
EC Number:
MDL number:
UNSPSC Code:
12164500
PubChem Substance ID:
E Number:
E300

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grade

analytical standard

Quality Level

form

solid

CofA

current certificate can be downloaded

feature

standard type water soluble vitamin

packaging

ampule of 1000 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

pH

1.0-2.5 (25 °C, 176 g/L in water)

mp

190-194 °C (dec.)

solubility

water: soluble 176 g/L at 20 °C

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Gene Information

human ... SLC23A2(9962)

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1 of 4

This Item
PHR1008W210901A4403
technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable, cell culture | plant: suitable

application(s)

food and beverages

application(s)

food and beverages

application(s)

flavors and fragrances

application(s)

-

form

solid

form

solid

form

crystalline, powder or crystals

form

powder

format

neat

format

neat

format

-

format

-

Quality Level

100

Quality Level

300

Quality Level

400

Quality Level

200

grade

analytical standard

grade

certified reference material, pharmaceutical secondary standard

grade

FG, Fragrance grade

grade

-

General description

L-Ascorbic acid plays the role of an antioxidant in plants in regulating the reactive oxygen species mechanism to form reduced peroxides.[1] It is present abundantly as a non-enzymatic antioxidant in higher plants.[1] It can be synthesized in a variety of plants and in all known mammals, except primates and guinea pigs.[2] It can commonly be used in the prevention of scurvy disease.[2]

Application

L-Ascorbic acid may be used as an analytical reference standard for the quantification of the analyte in fruits and vegetable juice samples using flow injection system with immobilised ascorbate oxidase enzyme.[3]
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Certificates of Analysis (COA)

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Greenberg.MD
Metabolic Pathways: Energetics, Tricarboxylic Acid Cycle, and Carbohydrates, (3), 2014-2014 null
Determination of L-ascorbic acid in fruit and vegetable juices by flow injection with immobilised ascorbate oxidase
Greenway MG and Ongomo P
Analyst, 115(10), 1297-1299 (1990)
Ascorbic acid deficiency leads to increased grain chalkiness in transgenic rice for suppressed of L-GalLDH
Yu L, et al.
Journal of Plant Physiology, 211, 13-26 (2017)
Takashi Yoshida et al.
Nature chemical biology, 2(11), 596-607 (2006-09-26)
Transient receptor potential (TRP) proteins form plasma-membrane cation channels that act as sensors for diverse cellular stimuli. Here, we report a novel activation mechanism mediated by cysteine S-nitrosylation in TRP channels. Recombinant TRPC1, TRPC4, TRPC5, TRPV1, TRPV3 and TRPV4 of
Noriko Umegaki-Arao et al.
Science translational medicine, 6(264), 264ra164-264ra164 (2014-11-28)
Revertant mosaicism is a naturally occurring phenomenon involving spontaneous correction of a pathogenic gene mutation in a somatic cell. It has been observed in several genetic diseases, including epidermolysis bullosa (EB), a group of inherited skin disorders characterized by blistering

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

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