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Methyl Paraben

Name: Methyl Paraben
Brand: SUPELCO

PESTANAL^®, analytical standard

Synonym(s):

Methyl 4-hydroxybenzoate, p-Hydroxybenzoic acid methyl ester, Methyl paraben, NIPAGIN

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About This Item

Linear Formula:

HOC₆H₄CO₂CH₃

CAS Number:

99-76-3

Molecular Weight:

152.15

UNSPSC Code:

12164500

E Number:

E218

PubChem Substance ID:

24871585

EC Number:

202-785-7

Beilstein/REAXYS Number:

509801

MDL number:

MFCD00002352

NACRES:

NA.24

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Properties

grade

analytical standard

Quality Segment

100

product line

PESTANAL^®

CofA

current certificate can be downloaded

packaging

ampule of 1000 mg

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

125-128 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

2-30°C

SMILES string

COC(=O)c1ccc(O)cc1

InChI

1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3

InChI key

LXCFILQKKLGQFO-UHFFFAOYSA-N

Gene Information

rat ... Ar(24208)

Description

General description

Methyl paraben is basically a methyl ester of p-hydroxybenzoic acid. It is non-toxic, and non-carcinogenic in nature. It is a stable, non-volatile compound and finds application as an anti-microbial preservative in foods, drugs and cosmetics. It is readily absorbed through the skin and gastrointestinal tract. Upon hydrolyzation, it is hydrolyzed to p-hydroxybenzoic acid, and the conjugates formed get rapidly excreted in the urine.

Methyl Paraben is a stable, non-volatile, methyl ester of p-hydroxybenzoic acid. It can find applications as a broad-spectrum antimicrobial preservative in foods, drugs and cosmetics. It is found to be noncarcinogenic and is highly effective against fungi like molds and yeast as well as bacteria.

Application

Methyl paraben was used a preservative standard in commercial food products, during an experimental investigation, done to study the application of microemulsion electrokinetic chromatography (MEEKC), in detecting food preservatives.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Show Differences

1 of 1

This Item	H3647	H6654	PHR1012
Supelco 47889 Methyl Paraben	Sigma-Aldrich H3647 Methyl 4-hydroxybenzoate	Sigma-Aldrich H6654 Methyl 4-hydroxybenzoate	Supelco PHR1012 Methylparaben
application(s) cleaning products cosmetics food and beverages personal care	application(s) -	application(s) -	application(s) cleaning products cosmetics flavors and fragrances food and beverages personal care pharmaceutical (small molecule)
technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) cell culture \| insect: suitable	technique(s) -	technique(s) HPLC: suitable, gas chromatography (GC): suitable
format neat	format -	format -	format neat
Quality Level 100	Quality Level 200	Quality Level 200	Quality Level 300
grade analytical standard	grade -	grade -	grade certified reference material, pharmaceutical secondary standard
storage temp. 2-30°C	storage temp. -	storage temp. -	storage temp. 2-30°C

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Hazard Classifications

Aquatic Chronic 2

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

334.4 °F

flash_point_c

168 °C

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Global Trade Item Number

SKU	GTIN
47889	04061838082541

Questions

1–5 of 5 Questions

Anonymous

10 months ago

How can I determine the shelf life / expiration / retest date of this product?

1 answer
1. Technical Support
  
  10 months ago
  
  If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
  For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
  For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
  For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
  
  Helpful?
Anonymous

a year ago

How is shipping temperature determined? And how is it related to the product storage temperature?

1 answer
1. Technical Support
  
  a year ago
  
  Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
  
  Helpful?
Anonymous

4 years ago

What is the Department of Transportation shipping information for this product?

1 answer
1. Technical Support
  
  4 years ago
  
  Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
  
  Helpful?
Anonymous

4 years ago

How is Product No. 47889 EPA 8040A Phenol Calibration Mix packaged?

1 answer
1. Technical Support
  
  4 years ago
  
  Product No. 47889 comes packaged in a 4ml amber vial with teflon lined solid cap.
  
  Helpful?
Anonymous

4 years ago

What is Product No. 47889 EPA 8040A Phenol Calibration Mix soluble in?

1 answer
1. Technical Support
  
  4 years ago
  
  Product No. 47889 EPA 8040A Phenol Calibration Mix is slightly soluble in water and soluble in alcohol, diethyl ether, and acetone
  
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