1,1,1-Trichloroethane solution

certified reference material, 200 μg/mL in methanol

Methyl chloroform
CAS Number:
EC Number:

Quality Level


certified reference material


current certificate can be downloaded


ampule of 1 mL


200 μg/mL in methanol


HPLC: suitable
gas chromatography (GC): suitable

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single component solution



InChI key


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General description

1,1,1-Trichloroethane is a dense and non-aqueous phase liquid, which can find wide applications as a solvent and stabilizer for vapor degreasing in industries.


Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Legal Information

TraceCERT is a registered trademark of Sigma-Aldrich Co. LLC

Signal Word


Target Organs



UN1230 - class 3 - PG 2 - Methanol

WGK Germany


Flash Point(F)

51.8 °F - closed cup

Flash Point(C)

11 °C - closed cup

Certificate of Analysis

Certificate of Origin

1, 4-Dioxane drinking water occurrence data from the third unregulated contaminant monitoring rule
Adamson.TD, et al.
The Science of the Total Environment, 596, 236-245 (2017)
Combination of zero-valent iron and anaerobic microorganisms immobilized in luffa sponge for degrading 1, 1, 1-trichloroethane and the relevant microbial community analysis
Wang W and Wu Y
Applied Microbiology and Biotechnology, 101, 783-796 (2017)
K T Bogen et al.
Regulatory toxicology and pharmacology : RTP, 10(1), 26-50 (1989-08-01)
A methodology for using physiologically based pharmacokinetic (PBPK) models to derive predicted safe concentrations of noncarcinogens in drinking water for humans based on experimentally determined no observed adverse effect levels (NOAELs) in animals is presented and applied to the case...
M J Hodgson et al.
Archives of internal medicine, 149(8), 1793-1798 (1989-08-01)
1,1,1-trichloroethane is a halogenated hydrocarbon solvent commonly used in industry because of its supposed lack of hepatotoxicity. Nonetheless, animal studies performed by several independent groups have shown the solvent to induce fat deposition, vacuolar degeneration, and centrilobular necrosis, changes similar...
Keith L Shelton
The Journal of pharmacology and experimental therapeutics, 333(2), 612-620 (2010-02-04)
The present study examined the involvement of the GABAA, N-methyl-D-aspartate (NMDA), nicotinic acetylcholine, and mu-opioid receptor systems in the transduction of the discriminative stimulus effects of the abused inhalant 1,1,1-trichloroethane (TCE). Sixteen B6SJLF1/J mice were trained to discriminate 10 min...

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