Luchun Duan et al.
Environment international, 70, 192-202 (2014-06-18)
Oral bioavailability of benzo[a]pyrene (B[a]P) was studied in a swine model using eight spiked soil samples after incubation for 50 and/or 90 days. Silica sand was used as a reference material and the relative bioavailability (RB) of B[a]P in soils...
K P Miller et al.
Drug metabolism reviews, 33(1), 1-35 (2001-03-29)
Polycyclic aromatic hydrocarbons are ubiquitous contaminants in the environment. Benzo[a]pyrene (BaP), a prototypical member of this class of chemicals, has been extensively studied for its toxic effects in laboratory animals and human populations. BaP toxicity is often mediated by oxidative...
Studies on the metabolism of benzo[a]pyrene and dose-dependent differences in the mutagenic profile of its ultimate carcinogenic metabolite.
A H Conney et al.
Drug metabolism reviews, 26(1-2), 125-163 (1994-01-01)
Emilien L Jamin et al.
PloS one, 8(3), e58591-e58591 (2013-03-14)
Colorectal neoplasia is the third most common cancer worldwide. Environmental factors such as diet are known to be involved in the etiology of this cancer. Several epidemiological studies have suggested that specific neo-formed mutagenic compounds related to meat consumption are...
Gunnar Boysen et al.
Mutation research, 543(1), 17-30 (2003-01-03)
We review studies which investigate the presence, using structure-specific analytical methods, of DNA or protein adducts of the carcinogen benzo[a]pyrene (BaP) in human tissues. The analytical methods include high performance liquid chromatography with fluorescence detection and gas chromatography-mass spectrometry. Although...