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502138

EPA 8270/Appendix IX Nitrosamines Mix

certified reference material, 2000 μg/mL each component in methanol

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.24

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grade

certified reference material, TraceCERT®

agency

EPA 8270

product line

TraceCERT®

CofA

current certificate can be downloaded

feature

standard type calibration

packaging

ampule of 1 mL

concentration

2000 μg/mL each component in methanol

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

environmental

format

multi-component solution

storage temp.

-10 to -25°C

Quality Level

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This Item
CRM484674737748913
technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

format

multi-component solution

format

multi-component solution

format

multi-component solution

format

multi-component solution

Quality Level

300

Quality Level

300

Quality Level

300

Quality Level

300

grade

certified reference material, TraceCERT®

grade

certified reference material, TraceCERT®

grade

certified reference material, TraceCERT®

grade

certified reference material, TraceCERT®

storage temp.

-10 to -25°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

concentration

2000 μg/mL each component in methanol

concentration

2000 μg/mL each component in methanol

concentration

2000 μg/mL each component in isopropanol

concentration

2000 μg/mL each component in hexane: toluene (1:1)

Application

EPA 8270/Appendix IX nitrosamines mix has been used as a standard solution in the determination of N-nitrosamine in water samples using gas chromatography coupled with mass spectrometry (GC-MS). It has also been used as a standard in the determination of nicotine and N-nitrosamines in indoor house dust using gas chromatography (GC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Legal Information

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

Analyte

Description

    N-Nitrosodibutylamine
    N-Nitrosodiethylamine
    N-Nitrosodimethylamine
    N-Nitrosodiphenylamine
    N-Nitrosodi-n-propylamine
    N-Nitrosomethylethylamine
    Nitrosomorpholine
    1-Nitrosopiperidine
    1-Nitrosopyrrolidine
    See All (9)

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Flam. Liq. 2 - Skin Sens. 1 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk

WGK 3


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Joy Roasa et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 36(3), 396-404 (2019-02-08)
A method to detect volatile nitrosamines in meat samples was developed using headspace sampling by solid-phase microextraction (HS-SPME), with analysis by GC-MS. A 50/30 µm divinylbenzene/carboxen/polydimethylsiloxane fused silica fibre was selected to extract a total of nine volatile nitrosamines: N-nitrosodimethylamine, N-nitrosomethylethylamine
Fully automated determination of N?nitrosamines in environmental waters by headspace solid?phase microextraction followed by GC?MS?MS
Llop A, et al.
Journal of Separation Science, 33, 3692-3700 (2010)
Wilson Beita-Sandí et al.
Chemosphere, 211, 1091-1097 (2018-09-19)
Cation exchange resins have proved to be efficient in removing precursors of N-nitrosodimethylamine (NDMA). NDMA is a probable human carcinogen with a calculated lifetime cancer risk of 10-6 at 0.7 ng/L in drinking water. This paper investigated the effect of pH and
Determination of nicotine and N-nitrosamines in house dust by pressurized liquid extraction and comprehensive gas chromatography?Nitrogen chemiluminiscence detection
Ramirez N, et al.
Journal of Chromatography A, 1219, 180-187 (2012)

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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