51569-U

Ascentis^® Express 90 Å RP-Amide (2 μm) HPLC Columns

Name: Ascentis<SUP>&#174;</SUP> Express 90 Å RP-Amide (2 μm) HPLC Columns
Brand: SUPELCO
Price: 931 USD
Availability: InStock

L × I.D. 5 cm × 2.1 mm UHPLC Column

Synonym(s):

Core-shell (SPP) Fused Core polar embedded HPLC column

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About This Item

UNSPSC Code:

41115700

NACRES:

SB.52

Key Documents

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Product Name

Ascentis^® Express RP-Amide, 2 μm UHPLC Column, 2 μm particle size, L × I.D. 5 cm × 2.1 mm

material

stainless steel column

Quality Level

100

agency

suitable for USP L60

product line

Ascentis^®

feature

endcapped

manufacturer/tradename

Ascentis^®

packaging

1 ea of

parameter

1000 bar max. pressure (14500 psi)
60 °C temp. range

technique(s)

HPLC: suitable
LC/MS: suitable
UHPLC-MS: suitable
UHPLC: suitable

L × I.D.

5 cm × 2.1 mm

surface area

120 m²/g

impurities

<5 ppm (metals)

matrix

Fused-Core particle platform
superficially porous particle

matrix active group

amide, alkyl phase

particle size

2 μm

pore size

90 Å pore size

pH

2-9

application(s)

food and beverages

separation technique

reversed phase

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This Item	51589-U	51588-U	51568-U
Supelco 51569-U Ascentis^® Express RP-Amide, 2 μm UHPLC Column	Supelco 51589-U Ascentis^® Express RP-Amide, 2 μm UHPLC Column	Supelco 51588-U Ascentis^® Express RP-Amide, 2 μm UHPLC Column	Supelco 51568-U Ascentis^® Express RP-Amide, 2 μm UHPLC Column
particle size 2 μm	particle size 2 μm	particle size 2 μm	particle size 2 μm
separation technique reversed phase	separation technique reversed phase	separation technique reversed phase	separation technique reversed phase
matrix active group amide, alkyl phase	matrix active group amide, alkyl phase	matrix active group amide, alkyl phase	matrix active group amide, alkyl phase
L × I.D. 5 cm × 2.1 mm	L × I.D. 15 cm × 3 mm	L × I.D. 10 cm × 3 mm	L × I.D. 3 cm × 2.1 mm
agency suitable for USP L60	agency suitable for USP L60	agency suitable for USP L60	agency suitable for USP L60
pore size 90 Å pore size	pore size 90 Å pore size	pore size 90 Å pore size	pore size 90 Å pore size

General description

Ascentis^® Express 2 μm RP-Amide is a high-speed, high-performance liquid chromatography column based on a new Fused-Core^® particle design. The fused core partical provides a thin porous shell of high-purity silica surrounding a solid silica core. This particle design exhibits very high column efficiency due to the shallow diffusion paths in the 0.4 micron thick porous shell and the small overall particle size of 2-microns. The one-step bonded, end-capped, amide-based polar-embedded stationary phase of Ascentis Express 2 μm RP-Amide provides, a stable, reversed phase packing with decreased hydrophobic character. Ascentis Express 2 μm RP-Amide can be used for basic, acidic, or neutral compounds with orthogonal selectivity from C18 or C8.

Other Notes

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Legal Information

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany

Fused-Core is a registered trademark of Advanced Materials Technology, Inc.

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A validated HPLC-MS/MS assay for quantifying unstable pharmacologically active metabolites of clopidogrel in human plasma: application to a clinical pharmacokinetic study.

Michael T Furlong et al.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 926, 36-41 (2013-04-02)

Clopidogrel is prescribed for the treatment of Acute Coronary Syndrome and recent myocardial infarction, recent stroke, or established peripheral arterial disease. A sensitive and reliable high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) assay was developed and validated to enable reliable

Simultaneous and confirmative detection of multi-residues of β₂-agonists and β-blockers in urine using LC-MS/MS/MS coupled with β-receptor molecular imprinted polymer SPE clean-up.

S Fan et al.

Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 30(12), 2093-2101 (2013-10-22)

A liquid chromatography-linear ion-trap spectrometry (LC-MS³) method using β-receptor molecular-imprinted polymer (MIP) solid-phase extraction (SPE) as clean-up was developed to determine simultaneously and confirmatively residues of 25 β₂-agonists and 21 β-blockers in urine samples. Urine samples were subjected to enzymatic

Simultaneous quantitative analyses of indole and oxindole alkaloids of Uncaria Hook in rat plasma and brain after oral administration of the traditional Japanese medicine Yokukansan using high-performance liquid chromatography with tandem mass spectrometry.

Hirotaka Kushida et al.

Biomedical chromatography : BMC, 27(12), 1647-1656 (2013-07-03)

Uncaria Hook (UH) alkaloids are involved in the beneficial effects of Yokukansan. However, the pharmacokinetics of UH alkaloids after oral administration of Yokukansan has not yet been sufficiently investigated. Therefore, we developed and validated a sensitive and specific high-performance liquid

Comparative study of new shell-type, sub-2 micron fully porous and monolith stationary phases, focusing on mass-transfer resistance.

Erzsébet Oláh et al.

Journal of chromatography. A, 1217(23), 3642-3653 (2010-04-23)

Today sub-2 microm packed columns are very popular to conduct fast chromatographic separations. The mass-transfer resistance depends on the particle size but some practical limits exist not to reach the theoretically expected plate height and mass-transfer resistance. Another approach applies

An HPLC-MS method for the quantification of new acetylcholinesterase inhibitor PC 48 (7-MEOTA-donepezil like compound) in rat plasma: Application to a pharmacokinetic study.

Martin Mzik et al.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1020, 85-89 (2016-04-01)

A simple, rapid and sensitive method based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) has been developed and validated for the quantitative determination in rat plasma of a new candidate for AD treatment, namely PC 48 (a 7-MEOTA-donepezil like compound) in

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Ascentis® Express 90 Å RP-Amide (2 μm) HPLC Columns