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Supel-Select HLB SPE Tube

bed wt. 60 mg, volume 3 mL, pk of 50



PE frit (20 μm)
polypropylene hardware

Quality Level


MS friendly


bed wt., 60 mg


pk of 50


3 mL


Hydrophilic modified styrene polymer particle platform

matrix active group

polystyrene phase

particle size

50-70 μm

pore size

80-200 Å pore size

surface area

160-420 m2/g


food and beverages

separation technique

reversed phase

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General description

Retention Mechanism: Reversed-phase
Sample Matrix Compatibility: Aqueous solutions (biological fluids, water)

  • Hydrophilic modified styrene polymer
  • Developed for the extraction of a highly broad range of compounds from aqueous samples
  • Retention predominately based on reversed-phase; however, because the phase is hydrophilic modified, it is amenable to polar compounds as well.
  • Examples of more polar compounds that are retained and recovered include (but not limited to): pyridoxine (logPo/w -0.56), riboflavin (logPo/w -2.02), biotin (logPo/w 0.11).


Supel-Select HLB SPE Tube may be used as an extraction cartridge for the solid phase extraction and determination of antibiotics in water samples using liquid chromatography electrospray ionization tandem mass spectrometry.

Features and Benefits

  • Excellent sample prep performance at a lower price
  • Amenable to generic methodology - save time, money, and headache during method development
  • Greater capacity allows for smaller bed weights = smaller elution volumes = time savings in sample processing
  • Resistance to overdrying allows for more robust methdology
  • Low UV and MS extractables for lower background and greater sensitivity
  • Stringent production and QC guidelines offer greater lot-to-lot, tube-to-tube, and well-to-well consistency for improved accuracy and precision

Legal Information

Supel is a trademark of Sigma-Aldrich Co. LLC

Storage Class Code

13 - Non Combustible Solids



Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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