Accurate protein binding affinities were measured using bioSPME more rapidly than membrane dialysis (RED) techniques. Binding affinities correlated to the reference values.
This study compares the use of SPME LC Tips to dried blood spots (DBS) in terms of extraction efficiency and detection limits of target analytes from whole blood.
This article highlights the impact that sample matrix effects can have on LC/MS response and discusses two novel approaches to reduce it.
LC/MS/MS Analysis of Drugs in Plasma on Ascentis® Express C18 after Extraction using SPME LC Tips
A demonstration of the use of innovative BioSPME fibers for the selective extraction of drugs and polar metbolites from biological matrices.