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575659-U

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HybridSPE®-PLus 96-Well Plate

volume 2 mL, pk of 1 ea

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Synonym(s):
HybridSPE®-PLus
NACRES:
NB.21

description

96-well Plate

Quality Level

product line

HybridSPE®

composition

bed wt., 50 mg

packaging

pk of 1 ea

technique(s)

solid phase extraction (SPE): suitable

volume

2 mL

matrix active group

zirconia-based phase

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This Item
575673-U575656-U55267-U
vibrant-m

575659-U

HybridSPE®-PLus 96-Well Plate

vibrant-m

575673-U

HybridSPE®-PLus 96-Well Plate

vibrant-m

575656-U

HybridSPE®-Phospholipid

vibrant-m

55267-U

HybridSPE®-Phospholipid

technique(s)

solid phase extraction (SPE): suitable

technique(s)

solid phase extraction (SPE): suitable

technique(s)

solid phase extraction (SPE): suitable

technique(s)

solid phase extraction (SPE): suitable

packaging

pk of 1 ea

packaging

pk of 20 ea

packaging

pk of 1

packaging

pk of 30

composition

bed wt., 50 mg

composition

bed wt., 50 mg

composition

bed wt., 50 mg

composition

bed wt., 500 mg

description

96-well Plate

description

96-well Plate

description

-

description

-

product line

HybridSPE®

product line

HybridSPE®

product line

HybridSPE®

product line

HybridSPE®

General description

HybridSPE-PLus is the next generation of HybridSPE-Phospholipid technology. The first of its kind, HybridSPE-Phospholipid technology was first introduced in 2008. It fuses the simple, standardized methodology of traditional protein precipitation with the specificity of solid phase extraction (SPE) for the simultaneous removal of proteins and phospholipids from biological samples prior to LC-MS analysis. Unlike other phospholipid removal products that use a hydrophobic retention mechanism to remove phsopholipids from biological samples, HybridSPE-Phospholipid technology uses a unique Lewis acid/base retention mechanism that allows it to separate phospholipids from even very hydrophobic analytes, such as vitamins, which are often retained along with phospholipids on competitive products.

Our HybridSPE-PLus products offer the same time-proven chemistry of our traditional HybridSPE-Phospholipid products coupled with manufacturing enhancements that stem from years of production experience. These manufacturing enhancements have allowed us to increase flow consistency and reduce sample hold up volumes, further improving analyte recoveries and assay reproducibility. We invite customers to take advantage of the newest technology; HybridSPE-PLus.

Features and Benefits

  • Simple 2-3 step standard methodology analogous to traditional protein precipitation provides simultaneous removal of both proteins and phospholipids
  • Unique Lewis acid/base retention mechanism effectively removes phospholipids from both hydrophilic and hydrophobic analytes of interest (unlike competitive chemistries) eliminating phospholipid-induced ion suppression
  • Highly reproducible, consistent product performance
  • Provides cleaner samples for longer column life and less instrument downtime
  • Available in 96-well and 1 mL cartridge dimensions

Legal Information

HybridSPE is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Customers Also Viewed

Slide 1 of 4

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Articles

This article highlights the impact that sample matrix effects can have on LC/MS response and discusses two novel approaches to reduce it.

Using HybridSPE-Phospholipid, Ascentis Express, and Other LC-MS Workflow Components

Protocols

Immunoassay-based methods for digitoxin or digoxin exist, but are time consuming, labor intensive, and not selective due to similarities in their chemical structures.

LC/MS/MS Analysis of Interacting Cardiac Drugs Digoxin, Quinidine, Amiodarone and Verapamil on Titan™ C18

Related Content

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Source a comprehensive range of quality reagents, reference materials and accessories for clinical and forensic testing across a range of testing methodologies including LC-MS, Molecular diagnostics and immunoassays. Bulk and customization options are available for enhancing efficiencies.

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Chromatograms

application for HPLC, application for SPE

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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