SUPELCOSIL LC-18 Supelguard Cartridge

5 μm particle size, L × I.D. 2 cm × 4 mm

Pricing and availability is not currently available.

Quality Level


suitable for USP L1


pkg of 1 kit


<70 °C temp. range


HPLC: suitable

L × I.D.

2 cm × 4 mm


silica gel high purity, spherical

matrix active group

C18 (octadecyl) phase

particle size

5 μm

pore size

120 Å

pH range

2 - 7.5

Featured Industry

Food and Beverages


use to protect LC-18, LC-PAH

separation technique

reversed phase

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SUPELCOSIL LC-18 Supelguard Cartridge may be used as a guard column along with SUPELCOSIL LC-18 HPLC Column during the analysis of:
  • Synthetic food dyes in commercial soft drinks by ion-pair high performance liquid chromatography (HPLC IP).
  • Drugs in plasma and brain samples by solid-phase extraction (SPE) and protein precipitation in conjunction with HPLC combined with ultraviolet (UV) detection.


Kit includes one cartridge, a stand-alone holder, a piece of tubing, and 2 nuts and ferrules.

Legal Information

SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
Supelguard is a trademark of Sigma-Aldrich Co. LLC
Certificate of Analysis
Certificate of Origin
Determination of synthetic food dyes in commercial soft drinks by TLC and ion-pair HPLC.
de Andrade FI, et al.
Food Chemistry, 157, 193-198 (2014)
Practice of solid-phase extraction and protein precipitation in the 96-well format combined with high-performance liquid chromatography-ultraviolet detection for the analysis of drugs in plasma and brain.
Rouan MC, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 754(1), 45-55 (2001)
L Marai et al.
Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire, 61(8), 840-849 (1983-08-01)
Natural triacylglycerols were resolved by high pressure liquid chromatography on Supelcosil LC-18 columns using a gradient of 30-90% propionitrile in acetonitrile as eluting solvent. The effluent was admitted to a quadrupole mass spectrometer via a direct liquid inlet interface. The...
Mert Ilhan et al.
Evidence-based complementary and alternative medicine : eCAM, 2014, 578103-578103 (2014-08-29)
The aim of the present research is to evaluate the antiurolithiatic effect of the various extracts prepared from the fruits of Viburnum opulus L., in regard to its ethnobotanical record. To induce urolithiasis, 70 mg/kg sodium oxalate was injected to the...
V Stocchi et al.
Analytical biochemistry, 146(1), 118-124 (1985-04-01)
A simple and rapid method for the determination of ATP, ADP, AMP, NADP+, NAD+, NADPH, and NADH in human erythrocytes is described. A single-step extraction procedure employing alkaline medium and CF 50A Amicon ultrafiltration membranes allows a simultaneous and total...

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