SUPELCOSIL LC-18 Supelguard Cartridge

5 μm particle size, L × I.D. 2 cm × 4 mm

Pricing and availability is not currently available.

Quality Level


suitable for USP L1


pkg of 2 ea


<70 °C temp. range


HPLC: suitable

L × I.D.

2 cm × 4 mm


silica gel high purity, spherical

matrix active group

C18 (octadecyl) phase

particle size

5 μm

pore size

120 Å

pH range

2 - 7.5

Featured Industry

Food and Beverages


use to protect LC-18, LC-PAH

separation technique

reversed phase

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General description

Guard columns are placed before the analytical column to protect and prevent harmful materials entering into the latter. It also helps as a backup to the in-line filter and also checks for leak through filter. The most suitable are short cartridge which is inserted into the cartridge holder.


SUPELCOSIL LC-18 Supelguard Cartridge was used as guard column for Supelcosil LC-18 HPLC column to analyze glucose tetrasaccharides in blood and urine samples using HPLC-electrospray ionization mass spectrometry (HPLC-ESI-MS). It was also suitable for analysing polar compounds in non-polar matrices using gas chromatography separation.

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Legal Information

SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
Supelguard is a trademark of Sigma-Aldrich Co. LLC
Certificate of Analysis
Certificate of Origin
Haoyue Zhang et al.
Clinical chemistry, 55(3), 527-532 (2009-02-03)
The isotope-labeled intravenous glucose tolerance test (IVGTT) combined with computer modeling is widely used to derive parameters related to glucose metabolism in vivo. Most of these methods involve use of either (2)H(2)-labeled or (13)C(1)-labeled D-glucose as a tracer with GC-MS...
Ike Jeon
Analyzing Food for Nutrition Labeling and Hazardous Contaminants , 95-95 (1994)
J Wu et al.
Journal of chromatography. A, 909(1), 37-52 (2001-02-24)
Polypyrrole (PPY) and poly-N-phenylpyrrole (PPPY) films were prepared and applied for solid-phase microextraction (SPME). The extraction properties of the new films to volatile organic compounds were examined using an SPME device coupled with GC-flame ionization detection. A PPY-coated capillary was...
L Marai et al.
Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire, 61(8), 840-849 (1983-08-01)
Natural triacylglycerols were resolved by high pressure liquid chromatography on Supelcosil LC-18 columns using a gradient of 30-90% propionitrile in acetonitrile as eluting solvent. The effluent was admitted to a quadrupole mass spectrometer via a direct liquid inlet interface. The...
Mert Ilhan et al.
Evidence-based complementary and alternative medicine : eCAM, 2014, 578103-578103 (2014-08-29)
The aim of the present research is to evaluate the antiurolithiatic effect of the various extracts prepared from the fruits of Viburnum opulus L., in regard to its ethnobotanical record. To induce urolithiasis, 70 mg/kg sodium oxalate was injected to the...
Amino Acid Analysis is the suitable tool for precise determination of protein quantities but also provides detailed information regarding the relative amino.
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