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Empore SPE 96-well Plate

matrix active group MPC, well volume 1.2 mL, pk of 1

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polypropylene filter (graded density)

Quality Level


(Mixed Phase Cation)


bed wt., 10-15 mg/well


pk of 1


CDS Analytical 70-2007-3983-0


solid phase extraction (SPE): suitable

bed volume

18 μL

membrane avg. diam.

5.5 mm

membrane thickness

0.75 mm

well volume

1.2 mL
1.2 mL

matrix active group

sulfonic acid bonding, benzene sulfonic acid

particle size

32 μm

pore size

60 Å pore size


0.07 meq/g capacity

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General description

Empore membrane SPE technology comprises of SPE particles tightly enmeshed within a network of inert PTFE fibrils (90% SPE particles : 10% PTFE, by weight). The SPE-membrane fabrication process results in a highly dense and uniform extraction medium that offers distinct advantages over traditional sorbent/packed-bed SPE products. Empore SPE technology provides a denser, more uniform extraction bed than traditional packed bed products allowing for smaller bed weights, shorter analyte to pore diffusion paths, and more efficient extractions.

The Empore 96-well line is ideal for high throughput SPE allowing users to process up to 96 samples in parallel. The unique Empore technology comprises of a series of polypropylene (PP) pre-filters that are layed on top of the SPE disk. The PP pre-filter acts as depth filter that provides faster flow-rates and reduces the risk of clogging.

Save Time & Money:
  • Reduced SPE Bed Mass = Reduced SPE Solvent & Elution Volumes
  • Minimize SPE eluate evaporation time
  • Potentially allows for direct injection of the SPE eluate
  • Dense & Uniform Extraction Medium = No SPE Channeling and Voiding
  • Efficient mass-transfer kinetics allow for faster flow rates
  • Eliminate SPE fines improving column and instrument life

Features and Benefits

  • Reduced elution volume (≤ 100 μL) allows for direct inject procedured or reduced eluate evaporation times
  • Allows for faster flow-rates without risk of recovery and reproducibility loss
  • Proprietary pre-filter reduces risk of clogging
  • Luer tip collar eliminates potential cross-contamination


Note: Empore 96-well SPE products are NOT compatible with Supelco PlatePrep vacuum manifolds (Cat. No. 57192-U and 575650-U). Empore 96-well vacuum manifold (Cat. No. 66879-U) is recommended for use with Empore 96-well products.

Other Notes

Developed for the highly selective extraction of basic (e.g., amines) compounds from difficult sample matrices such as biological fluids (e.g., plasma, urine). Also allows researchers to fractionate basic compounds from neutral/acidic compounds.

Legal Information

Empore is a trademark of CDS Analytical


CDS Analytical LLC recently acquired the rights to Empore products from 3M Purification Inc. For an interim phase, you may receive products packaged with either manfacturer′s branding.

Storage Class

11 - Combustible Solids




Not applicable


Not applicable

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