BP1100

Hydroxychloroquine sulfate

British Pharmacopoeia (BP) Reference Standard

• Synonym(s): 7-Chloro-4-[4-(N-ethyl-N-b-hydroxyethylamino)-1-methylbutylamino]quinoline sulfate
• Empirical Formula (Hill Notation): C₁₈H₂₆ClN₃O · H₂SO₄
• CAS Number: 747-36-4
• Molecular Weight: 433.95
• MDL number: MFCD00078203
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• agency: BP
• API family: hydroxychloroquine
• form: solid
• shelf life: limited shelf life, expiry date on the label
• packaging: pkg of 100 mg
• manufacturer/tradename: BP
• color: off-white
• mp: 238-241 °C
• solubility: water: soluble
• application(s): pharmaceutical; pharmaceutical small molecule
• format: neat
• shipped in: ambient
• storage temp.: 2-8°C
• SMILES string: OS(O)(=O)=O.CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12
• InChI: 1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)
• InChI key: JCBIVZZPXRZKTI-UHFFFAOYSA-N
• Gene Information: human ... TLR7(51284), TLR9(54106)

Description

General description

Hydroxychloroquine Sulfate (Hydroxychloroquine Sulphate) is a salt of hydroxychloroquine (HCQ, Plaquenil), a 4-aminoquinoline based antiviral drug.[1][2][3][4][4][5]
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Hydroxychloroquine sulfate BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Hydroxychloroquine Tablets

Biochem/physiol Actions

Hydroxychloroquine sulfate is an anti-inflammatory (via TNF), disease-modifying antirheumatic drug (DMARD), and a heme polymerase inhibitor.

Hydroxychloroquine sulfate is an anti-inflammatory (via TNF), disease-modifying antirheumatic drug (DMARD), and a heme polymerase inhibitor. It is used in treating malaria.

Packaging

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H315,H319
• pcodes: P264 - P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable